Table 1 Markers of human HSCs Markers .... | American Society of Hematology

Table 1

Markers of human HSCs

Markers	SRC frequency	Mouse	Time point to assess HSC function (weeks)	Reference
CD34⁺
Lin⁻CD34⁺CD38⁻	1 in 617	NS	6-9	22
Lin⁻CD34⁺CD38⁻ρ(low)	1 in 30	NS	7-10	27
Lin⁻CD34⁺CD38⁻CD90⁺CD45RA⁻	1 in 10	NOG	12	26
Lin⁻CD34⁺CD38⁻CD45RA⁻Thy1⁺ρ(low)CD49f⁺	1 in a few	NSG	20 + serial transplant	28
CD34⁻
Lin⁻CD34⁻CD38⁻CD93⁺	1 in 7500	NS	8-10	29
Lin⁻CD34⁻CD38⁻CD93⁺	1 in 6100	NSG	ND	30
18Lin⁻CD34⁻CD133⁺	1 in 142	NOG	12	31

Markers	SRC frequency	Mouse	Time point to assess HSC function (weeks)	Reference
CD34⁺
Lin⁻CD34⁺CD38⁻	1 in 617	NS	6-9	22
Lin⁻CD34⁺CD38⁻ρ(low)	1 in 30	NS	7-10	27
Lin⁻CD34⁺CD38⁻CD90⁺CD45RA⁻	1 in 10	NOG	12	26
Lin⁻CD34⁺CD38⁻CD45RA⁻Thy1⁺ρ(low)CD49f⁺	1 in a few	NSG	20 + serial transplant	28
CD34⁻
Lin⁻CD34⁻CD38⁻CD93⁺	1 in 7500	NS	8-10	29
Lin⁻CD34⁻CD38⁻CD93⁺	1 in 6100	NSG	ND	30
18Lin⁻CD34⁻CD133⁺	1 in 142	NOG	12	31

18Lin⁻, 18 lineage marker-negative; ND, not described; NOG, NOD/SCID IL2 receptor γ null; NS, NOD/SCID; NSG, NOD/SCID IL2 receptor γ^−/−; SRC, SCID repopulating cells.