Thromboelastometry analysis of mouse whole blood with or without the addition of procoagulant protein
Mouse . | Protein . | CT (s) . | α angle (°) . | MCF (mm) . | N . |
---|---|---|---|---|---|
WT | None | 180 ± 50 | 68 ± 4 | 56 ± 1 | 7 |
HB | None | 4387 ± 1263 | ND | 2 ± 3 | 4 |
HB | mFVIIa | 191 ± 86 | 70 ± 3 | 60 ± 2 | 4 |
HB | mFVIIa-FMR | 180 ± 101 | 64 ± 5 | 59 ± 1 | 4 |
Mouse . | Protein . | CT (s) . | α angle (°) . | MCF (mm) . | N . |
---|---|---|---|---|---|
WT | None | 180 ± 50 | 68 ± 4 | 56 ± 1 | 7 |
HB | None | 4387 ± 1263 | ND | 2 ± 3 | 4 |
HB | mFVIIa | 191 ± 86 | 70 ± 3 | 60 ± 2 | 4 |
HB | mFVIIa-FMR | 180 ± 101 | 64 ± 5 | 59 ± 1 | 4 |
All values are shown as mean ± SD. Procoagulant was added at a final concentration of 1 µg/mL in blood, prior to the assay. CT, clot time; HB, hemophilia B mouse; MCF, maximum clot firmness; N, number of samples assayed; ND, not determined; WT, wild-type mouse.