Table 1

Mendelian breeding ratios of R41A mice

Genotype
Breeding strategy+/++/+; PF4-Crefl/+fl/+; PF4-Crefl/flfl/fl; PF4-CreTotal
fl/+;PF4-Cre × fl/+;PF4-Cre        
 Expected frequency 6.25% 18.75% 12.50% 37.50% 6.25% 18.75% 100.00% 
 Actual count 15 51 28 118 19 24 255 
 Actual frequency 5.88% 20.00% 10.98% 46.27% 7.45% 9.41% 100.00% 
fl/fl × fl/+;PF4-Cre        
 Expected frequency 0% 0% 25% 25% 25% 25% 100% 
 Actual count 0 0 16 14 14 6 50 
 Actual frequency 0% 0% 32% 28% 28% 12% 100% 
Genotype
Breeding strategy+/++/+; PF4-Crefl/+fl/+; PF4-Crefl/flfl/fl; PF4-CreTotal
fl/+;PF4-Cre × fl/+;PF4-Cre        
 Expected frequency 6.25% 18.75% 12.50% 37.50% 6.25% 18.75% 100.00% 
 Actual count 15 51 28 118 19 24 255 
 Actual frequency 5.88% 20.00% 10.98% 46.27% 7.45% 9.41% 100.00% 
fl/fl × fl/+;PF4-Cre        
 Expected frequency 0% 0% 25% 25% 25% 25% 100% 
 Actual count 0 0 16 14 14 6 50 
 Actual frequency 0% 0% 32% 28% 28% 12% 100% 
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