Outcome features of MRC ALL97/99 and UKALL2003 patients with BCP-ALL and IR cytogenetics stratified according to CNA risk profile
| Outcome measures . | IR cytogenetic patients . | ||||||
|---|---|---|---|---|---|---|---|
| ALL97/99 10-y rate (99% CI) . | UKALL2003 5-y rate (99% CI) . | ||||||
| CNA-GR profile group A . | CNA-IR/PR profile group B . | P . | CNA-GR profile group A . | CNA-IR/PR profile group B . | P . | ||
| EFS | 78% (66-86) | 57% (45-66) | <.001 | 96% (85-99) | 82% (72-89) | <.001 | |
| Relapse risk | 17% (10-29) | 39% (29-51) | <.001 | 3% (1-14) | 14% (8-25) | .001 | |
| OS | 84% (72-91) | 70% (59-79) | .001 | 98% (89-100) | 87% (76-93) | .001 | |
| Outcome measures . | IR cytogenetic patients . | ||||||
|---|---|---|---|---|---|---|---|
| ALL97/99 10-y rate (99% CI) . | UKALL2003 5-y rate (99% CI) . | ||||||
| CNA-GR profile group A . | CNA-IR/PR profile group B . | P . | CNA-GR profile group A . | CNA-IR/PR profile group B . | P . | ||
| EFS | 78% (66-86) | 57% (45-66) | <.001 | 96% (85-99) | 82% (72-89) | <.001 | |
| Relapse risk | 17% (10-29) | 39% (29-51) | <.001 | 3% (1-14) | 14% (8-25) | .001 | |
| OS | 84% (72-91) | 70% (59-79) | .001 | 98% (89-100) | 87% (76-93) | .001 | |