Table 1

Characteristics of the patients

CharacteristicValueValue
Training datasetValidation
No. of patients 86 181 
Male sex, no. of patients (%) 55 (64) 107 (59) 
Rai stage   
 0-II 60 (70) 154 (85) 
 III-IV 9 (10) 6 (3) 
 No data 17 (20) 21 (12) 
Age at diagnosis, y   
 Median 56 56 
 Range 34-78 34-81 
ZAP-70 expression   
 ZAP-70 negative (0% to 20%) 41 (48) 110 (61) 
 ZAP-70 positive (>20%) 45 (52) 71 (39) 
IGHV   
 Unmutated (≥98% homology) 43 (50) 81 (45) 
 Mutated (<98%homology) 43 (50) 100 (55) 
CharacteristicValueValue
Training datasetValidation
No. of patients 86 181 
Male sex, no. of patients (%) 55 (64) 107 (59) 
Rai stage   
 0-II 60 (70) 154 (85) 
 III-IV 9 (10) 6 (3) 
 No data 17 (20) 21 (12) 
Age at diagnosis, y   
 Median 56 56 
 Range 34-78 34-81 
ZAP-70 expression   
 ZAP-70 negative (0% to 20%) 41 (48) 110 (61) 
 ZAP-70 positive (>20%) 45 (52) 71 (39) 
IGHV   
 Unmutated (≥98% homology) 43 (50) 81 (45) 
 Mutated (<98%homology) 43 (50) 100 (55) 
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