Table 3

SWiTCH brain MRI results by MRA vessel occlusion grading score

MRA severity grade
Left hemisphereRight hemisphere
01-34-601-34-6
Baseline       
 No. of subjects 63 79 81 61 
 Subcortical 46 (73%) 7 (88%) 74 (94%)* 60 (74%) 7 (88%) 51 (84%) 
 Cortical Infarct 23 (37%) 5 (63%) 52 (66%)* 19 (23%) 3 (38%) 34 (56%)* 
 Cortical and subcortical 20 (32%) 5 (63%) 50 (63%)* 18 (22%) 3 (38%) 31(51%)* 
On study       
 Stroke 1 (2%) 2 (3%) 1 (1%) 3 (3%) 
End of study       
 No. of subjects 50 54 62 43 
 Subcortical 39 (78%) 7 (88%) 50 (93%) 45 (73%) 7 (100%) 36 (84%) 
 Cortical Infarct 21 (42%) 4 (50%) 34 (63%) 17 (27%) 3 (43%) 24 (56%)* 
 Cortical and subcortical 18 (36%) 4 (50%) 32 (59%) 16 (26%) 3 (43%) 21 (49%)* 
MRA severity grade
Left hemisphereRight hemisphere
01-34-601-34-6
Baseline       
 No. of subjects 63 79 81 61 
 Subcortical 46 (73%) 7 (88%) 74 (94%)* 60 (74%) 7 (88%) 51 (84%) 
 Cortical Infarct 23 (37%) 5 (63%) 52 (66%)* 19 (23%) 3 (38%) 34 (56%)* 
 Cortical and subcortical 20 (32%) 5 (63%) 50 (63%)* 18 (22%) 3 (38%) 31(51%)* 
On study       
 Stroke 1 (2%) 2 (3%) 1 (1%) 3 (3%) 
End of study       
 No. of subjects 50 54 62 43 
 Subcortical 39 (78%) 7 (88%) 50 (93%) 45 (73%) 7 (100%) 36 (84%) 
 Cortical Infarct 21 (42%) 4 (50%) 34 (63%) 17 (27%) 3 (43%) 24 (56%)* 
 Cortical and subcortical 18 (36%) 4 (50%) 32 (59%) 16 (26%) 3 (43%) 21 (49%)* 

Percentages represent the proportion of subjects with an MRI lesion for a given MRA vasculopathy grade range.

*

P < .05 using the χ2 test.

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