Table 3

Platelet diameters for distinguishing IT with giant platelets

CutoffAUCSensitivity %95% CISpecificity %95% CI
MPD μm >3.74 0.9154 86 79 to 91 87 82 to 90 
PDDW μm >4.27 0.8812 80 72 to 86 83 78 to 88 
PDLCR % >39.80 0.9208 85 78 to 91 87 83 to 90 
MPD μm and PDLCR % >3.74 and >39.8 0.9991 98 93 to 99 99 97 to 100 
CutoffAUCSensitivity %95% CISpecificity %95% CI
MPD μm >3.74 0.9154 86 79 to 91 87 82 to 90 
PDDW μm >4.27 0.8812 80 72 to 86 83 78 to 88 
PDLCR % >39.80 0.9208 85 78 to 91 87 83 to 90 
MPD μm and PDLCR % >3.74 and >39.8 0.9991 98 93 to 99 99 97 to 100 

Area under the curve (AUC), sensitivity and specificity of best cutoff levels for MPD, PDDW, and PDLCR identified by receiver operating characteristic analysis in discriminating hMYH9-RD, tMYH9-RD, and bBSS from all other examined forms of thrombocytopenia.

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