IVIG-treated pregnancies and therapy effectiveness
AUC . | Therapy failure: 21 newborns <50 × 109/L . | Therapy success: 38 newborns ≥50 × 109/L . | P . | Sensitivity, % . | Specificity, % . | PPV, % . | NPV, % . |
---|---|---|---|---|---|---|---|
Gestation ≥ 2 | |||||||
<23 IU/mL | 5 | 30 | .0001 | 76.19 | 78.95 | 66.67 | 85.71 |
≥23 IU/mL | 16 | 8 | |||||
Gestation = 2 (n = 22) | |||||||
<23 IU/mL | 0 | 15 | .0017 | 100.00 | 83.36 | 62.50 | 100.00 |
≥23 IU/mL | 5 | 3 | |||||
Gestation > 2 (n = 37) | |||||||
<23 IU/mL | 5 | 15 | .0171 | 68.75 | 75.00 | 68.75 | 75.00 |
≥23 IU/mL | 11 | 5 |
AUC . | Therapy failure: 21 newborns <50 × 109/L . | Therapy success: 38 newborns ≥50 × 109/L . | P . | Sensitivity, % . | Specificity, % . | PPV, % . | NPV, % . |
---|---|---|---|---|---|---|---|
Gestation ≥ 2 | |||||||
<23 IU/mL | 5 | 30 | .0001 | 76.19 | 78.95 | 66.67 | 85.71 |
≥23 IU/mL | 16 | 8 | |||||
Gestation = 2 (n = 22) | |||||||
<23 IU/mL | 0 | 15 | .0017 | 100.00 | 83.36 | 62.50 | 100.00 |
≥23 IU/mL | 5 | 3 | |||||
Gestation > 2 (n = 37) | |||||||
<23 IU/mL | 5 | 15 | .0171 | 68.75 | 75.00 | 68.75 | 75.00 |
≥23 IU/mL | 11 | 5 |
P calculated with Fisher’s exact test.
NPV, negative predictive value; PPV, positive predictive value.