Table 1

IVIG-treated pregnancies and therapy effectiveness

AUCTherapy failure: 21 newborns <50 × 109/LTherapy success: 38 newborns ≥50 × 109/LPSensitivity, %Specificity, %PPV, %NPV, %
Gestation ≥ 2 
 <23 IU/mL 30 .0001 76.19 78.95 66.67 85.71 
 ≥23 IU/mL 16 
Gestation = 2 (n = 22) 
 <23 IU/mL 15 .0017 100.00 83.36 62.50 100.00 
 ≥23 IU/mL 
Gestation > 2 (n = 37) 
 <23 IU/mL 15 .0171 68.75 75.00 68.75 75.00 
 ≥23 IU/mL 11 
AUCTherapy failure: 21 newborns <50 × 109/LTherapy success: 38 newborns ≥50 × 109/LPSensitivity, %Specificity, %PPV, %NPV, %
Gestation ≥ 2 
 <23 IU/mL 30 .0001 76.19 78.95 66.67 85.71 
 ≥23 IU/mL 16 
Gestation = 2 (n = 22) 
 <23 IU/mL 15 .0017 100.00 83.36 62.50 100.00 
 ≥23 IU/mL 
Gestation > 2 (n = 37) 
 <23 IU/mL 15 .0171 68.75 75.00 68.75 75.00 
 ≥23 IU/mL 11 

P calculated with Fisher’s exact test.

NPV, negative predictive value; PPV, positive predictive value.

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