Table 3

Differential gene expression by response to imexon

GeneNPAdjusted FDR
CD68 13 <.0001 0.0001 
Glutathione peroxidase 1 (GPX113 .0007 0.0126 
Mn superoxide dismutase (SOD213 .0009 0.0126 
Thioredoxin (TXN13 .0052 0.0546 
Glutathione peroxidase 4 (GPX413 .0090 0.0756 
Glutathione peroxidase 3 (GPX313 .0109 0.0763 
HLA-DRA 13 .0334 0.2004 
Peroxiredoxin 4 (PRDX413 .0640 0.3360 
Cyclin D2 (CCND213 .0745 0.3477 
Peroxiredoxin 3 (PRDX313 .1270 0.4778 
CD19 12 .1299 0.4778 
Protein tyrosine phosphatase, nonreceptor 1 (PTPN113 .1365 0.4778 
HLA-DRB1 13 .1719 0.5244 
CD3D 12 .1748 0.5244 
Transferrin receptor (TFRC13 .2058 0.5762 
Cytochrome c oxidase subunit IV isoform 1 (COX4I113 .2644 0.6941 
Catalase (CAT13 .3045 0.7242 
Inositol-trisphosphate 3-kinase B (ITPKB13 .3181 0.7242 
Membrane-spanning 4-domains, A1 (MS4A113 .3335 0.7242 
Interferon regulatory factor 4 (IRF413 .3518 0.7242 
Aldo-keto reductase family 1, C3 (AKR1C312 .3662 0.7242 
Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD113 .4091 0.7242 
B-cell leukemia/lymphoma 2 (BCL213 .4232 0.7242 
Myeloblastosis viral oncogene homolog-like 1 (MYBL111 .4253 0.7242 
Cu, Zn superoxide dismutase (SOD113 .4473 0.7242 
Lymphoid-restricted membrane protein (LRMP13 .4483 0.7242 
Thioredoxin reductase 1 (TXNRD113 .5045 0.7466 
Glutathione S-transferase μ 1 (GSTM113 .5107 0.7466 
Fucosyltransferase 8 (FUT813 .5155 0.7466 
Thioredoxin 2 (TXN213 .6185 0.8634 
Glutathione S-transferase π 1 (GSTP113 .6373 0.8634 
LIM domain only 2 (LMO212 .7442 0.9162 
Membrane metalloendopeptidase (MME13 .7489 0.9162 
Microsomal glutathione S-transferase 1 (MGST113 .7564 0.9162 
MYC 13 .7635 0.9162 
Glutathione S-transferase α 1 (GSTA1.8088 0.9296 
Myeloperoxidase (MPO12 .8281 0.9296 
Extracellular superoxide dismutase (SOD313 .8411 0.9296 
B-cell leukemia/lymphoma 6 (BCL613 .8985 0.9498 
Thioredoxin reductase 2 (TXNRD213 .9046 0.9498 
Interleukin 16 (IL1613 .9525 0.9661 
Thioredoxin interacting protein (TXNIP13 .9661 0.9661 
GeneNPAdjusted FDR
CD68 13 <.0001 0.0001 
Glutathione peroxidase 1 (GPX113 .0007 0.0126 
Mn superoxide dismutase (SOD213 .0009 0.0126 
Thioredoxin (TXN13 .0052 0.0546 
Glutathione peroxidase 4 (GPX413 .0090 0.0756 
Glutathione peroxidase 3 (GPX313 .0109 0.0763 
HLA-DRA 13 .0334 0.2004 
Peroxiredoxin 4 (PRDX413 .0640 0.3360 
Cyclin D2 (CCND213 .0745 0.3477 
Peroxiredoxin 3 (PRDX313 .1270 0.4778 
CD19 12 .1299 0.4778 
Protein tyrosine phosphatase, nonreceptor 1 (PTPN113 .1365 0.4778 
HLA-DRB1 13 .1719 0.5244 
CD3D 12 .1748 0.5244 
Transferrin receptor (TFRC13 .2058 0.5762 
Cytochrome c oxidase subunit IV isoform 1 (COX4I113 .2644 0.6941 
Catalase (CAT13 .3045 0.7242 
Inositol-trisphosphate 3-kinase B (ITPKB13 .3181 0.7242 
Membrane-spanning 4-domains, A1 (MS4A113 .3335 0.7242 
Interferon regulatory factor 4 (IRF413 .3518 0.7242 
Aldo-keto reductase family 1, C3 (AKR1C312 .3662 0.7242 
Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD113 .4091 0.7242 
B-cell leukemia/lymphoma 2 (BCL213 .4232 0.7242 
Myeloblastosis viral oncogene homolog-like 1 (MYBL111 .4253 0.7242 
Cu, Zn superoxide dismutase (SOD113 .4473 0.7242 
Lymphoid-restricted membrane protein (LRMP13 .4483 0.7242 
Thioredoxin reductase 1 (TXNRD113 .5045 0.7466 
Glutathione S-transferase μ 1 (GSTM113 .5107 0.7466 
Fucosyltransferase 8 (FUT813 .5155 0.7466 
Thioredoxin 2 (TXN213 .6185 0.8634 
Glutathione S-transferase π 1 (GSTP113 .6373 0.8634 
LIM domain only 2 (LMO212 .7442 0.9162 
Membrane metalloendopeptidase (MME13 .7489 0.9162 
Microsomal glutathione S-transferase 1 (MGST113 .7564 0.9162 
MYC 13 .7635 0.9162 
Glutathione S-transferase α 1 (GSTA1.8088 0.9296 
Myeloperoxidase (MPO12 .8281 0.9296 
Extracellular superoxide dismutase (SOD313 .8411 0.9296 
B-cell leukemia/lymphoma 6 (BCL613 .8985 0.9498 
Thioredoxin reductase 2 (TXNRD213 .9046 0.9498 
Interleukin 16 (IL1613 .9525 0.9661 
Thioredoxin interacting protein (TXNIP13 .9661 0.9661 
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