Table 2

Predictors of successful ITI

Clinical characteristics
Younger age34  
Inhibitor titer <10 BU/mL before start of ITI32-34  
Historical peak titer <200 BU/mL32  
Peak titer after start of ITI <100 BU/mL32  
<5 y between diagnosis of inhibitor and start of ITI34  
Low-risk F8 genotype (small insertions, small deletions, and missense mutations)32  
Clinical characteristics
Younger age34  
Inhibitor titer <10 BU/mL before start of ITI32-34  
Historical peak titer <200 BU/mL32  
Peak titer after start of ITI <100 BU/mL32  
<5 y between diagnosis of inhibitor and start of ITI34  
Low-risk F8 genotype (small insertions, small deletions, and missense mutations)32  

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