Candidate surface molecules highly correlating with EVI1 expression
| Symbol . | Official gene name . | Probe ID . | Fold change . |
|---|---|---|---|
| PTPRD | Protein tyrosine phosphatase, receptor type, D | 213362_at | 2.679 |
| 214043_at | 2.514 | ||
| 205712_at | 1.685 | ||
| ITGA2B* | Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | 206494_s_at | 2.573 |
| 216956_s_at | 1.812 | ||
| 206493_at | 1.806 | ||
| HTR1F | 5-Hydroxytryptamine (serotonin) receptor 1F, G protein coupled | 221458_at | 2.119 |
| ITGB3* | Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 204627_s_at | 1.970 |
| 204625_s_at | 1.438 | ||
| PEAR1* | Platelet endothelial aggregation receptor 1 | 228618_at | 1.944 |
| NRN1 | Neuritin 1 | 218625_at | 1.867 |
| GPR56 | G protein-coupled receptor 56 | 212070_at | 1.839 |
| 206582_s_at | 1.679 | ||
| CMTM8 | CKLF-like MARVEL transmembrane domain containing 8 | 235099_at | 1.618 |
| ABCA1 | ATP-binding cassette, subfamily A (ABC1), member 1 | 203504_s_at | 1.513 |
| SELP* | Selectin P (granule membrane protein 140 kDa, antigen CD62) | 206049_at | 1.495 |
| MPL* | Myeloproliferative leukemia virus oncogene | 207550_at | 1.404 |
| Symbol . | Official gene name . | Probe ID . | Fold change . |
|---|---|---|---|
| PTPRD | Protein tyrosine phosphatase, receptor type, D | 213362_at | 2.679 |
| 214043_at | 2.514 | ||
| 205712_at | 1.685 | ||
| ITGA2B* | Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | 206494_s_at | 2.573 |
| 216956_s_at | 1.812 | ||
| 206493_at | 1.806 | ||
| HTR1F | 5-Hydroxytryptamine (serotonin) receptor 1F, G protein coupled | 221458_at | 2.119 |
| ITGB3* | Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 204627_s_at | 1.970 |
| 204625_s_at | 1.438 | ||
| PEAR1* | Platelet endothelial aggregation receptor 1 | 228618_at | 1.944 |
| NRN1 | Neuritin 1 | 218625_at | 1.867 |
| GPR56 | G protein-coupled receptor 56 | 212070_at | 1.839 |
| 206582_s_at | 1.679 | ||
| CMTM8 | CKLF-like MARVEL transmembrane domain containing 8 | 235099_at | 1.618 |
| ABCA1 | ATP-binding cassette, subfamily A (ABC1), member 1 | 203504_s_at | 1.513 |
| SELP* | Selectin P (granule membrane protein 140 kDa, antigen CD62) | 206049_at | 1.495 |
| MPL* | Myeloproliferative leukemia virus oncogene | 207550_at | 1.404 |
Genes localized at the cell-surface membrane were extracted from the 42 candidate genes identified in Figure 1A. Fold changes calculated from the microarray data of human AML samples are shown.
These genes represent surface markers of megakaryocyte and platelet lineage.