OR and 95% CI for mtDNA copy number and B-NHL overall and subtype of CLL according to follow-up time
| . | Logistic regression . | ||||
|---|---|---|---|---|---|
| Q1 (6.7-23.6) . | Q2 (23.7-29.4) . | Q3 (29.5-36.2) . | Q4 (36.3-294.7) . | P trend . | |
| B-NHL* | |||||
| ≤4.6 y follow-up | |||||
| n (case/control) | 48/50 | 43/56 | 38/47 | 77/53 | |
| Adjusted OR (95% CI) | Ref. | 0.81 (0.40-1.62) | 0.87 (0.42-1.80) | 1.34 (0.71-2.55) | .18 |
| >4.6 y follow-up | |||||
| n | 64/57 | 34/49 | 47/57 | 67/49 | |
| Adjusted OR (95% CI) | Ref. | 0.52 (0.28-0.96) | 0.75 (0.41-1.36) | 1.16 (0.62-2.16) | .53 |
| B-NHL without MM* | |||||
| ≤4.6 y follow-up | |||||
| n | 32/38 | 28/37 | 26/33 | 58/36 | |
| Adjusted OR (95% CI) | Ref. | 1.00 (0.44-2.27) | 1.25 (0.50-3.11) | 2.09 (0.97-4.51) | .02 |
| >4.6 y follow-up | |||||
| n | 50/46 | 27/35 | 35/48 | 53/36 | |
| Adjusted OR (95% CI) | Ref. | 0.63 (0.31-1.27) | 0.60 (0.30-1.18) | 1.31 (0.65-2.62) | .59 |
| CLL† | |||||
| ≤4.6 y follow-up | |||||
| n | 6/117 | 8/117 | 8/118 | 26/117 | |
| Adjusted OR (95% CI) | Ref. | 1.24 (0.41-3.68) | 1.46 (0.49-4.35) | 3.70 (1.44-9.52) | .001 |
| >4.6 y follow-up | |||||
| n | 8/117 | 12/117 | 13/118 | 21/117 | |
| Adjusted OR (95% CI) | Ref. | 1.40 (0.56-3.52) | 1.43 (0.58-3.54) | 2.39 (0.99-5.78) | .05 |
| . | Logistic regression . | ||||
|---|---|---|---|---|---|
| Q1 (6.7-23.6) . | Q2 (23.7-29.4) . | Q3 (29.5-36.2) . | Q4 (36.3-294.7) . | P trend . | |
| B-NHL* | |||||
| ≤4.6 y follow-up | |||||
| n (case/control) | 48/50 | 43/56 | 38/47 | 77/53 | |
| Adjusted OR (95% CI) | Ref. | 0.81 (0.40-1.62) | 0.87 (0.42-1.80) | 1.34 (0.71-2.55) | .18 |
| >4.6 y follow-up | |||||
| n | 64/57 | 34/49 | 47/57 | 67/49 | |
| Adjusted OR (95% CI) | Ref. | 0.52 (0.28-0.96) | 0.75 (0.41-1.36) | 1.16 (0.62-2.16) | .53 |
| B-NHL without MM* | |||||
| ≤4.6 y follow-up | |||||
| n | 32/38 | 28/37 | 26/33 | 58/36 | |
| Adjusted OR (95% CI) | Ref. | 1.00 (0.44-2.27) | 1.25 (0.50-3.11) | 2.09 (0.97-4.51) | .02 |
| >4.6 y follow-up | |||||
| n | 50/46 | 27/35 | 35/48 | 53/36 | |
| Adjusted OR (95% CI) | Ref. | 0.63 (0.31-1.27) | 0.60 (0.30-1.18) | 1.31 (0.65-2.62) | .59 |
| CLL† | |||||
| ≤4.6 y follow-up | |||||
| n | 6/117 | 8/117 | 8/118 | 26/117 | |
| Adjusted OR (95% CI) | Ref. | 1.24 (0.41-3.68) | 1.46 (0.49-4.35) | 3.70 (1.44-9.52) | .001 |
| >4.6 y follow-up | |||||
| n | 8/117 | 12/117 | 13/118 | 21/117 | |
| Adjusted OR (95% CI) | Ref. | 1.40 (0.56-3.52) | 1.43 (0.58-3.54) | 2.39 (0.99-5.78) | .05 |
Quartiles (Q) number (minimum-maximum); P trend is the P value (2 sided) calculated by including the quartile number as a continuous variable.
Ref., reference.
Conditional logistic regression model adjusted for smoking status and educational level.
Unconditional logistic regression model adjusted for age at recruitment, sex, country, smoking status, educational level, and plate number.