Table 2

Analysis of VDJ gene rearrangements in clonal B-cell lymphomas of miR-217KI mice

Mouse ID*V geneD geneJ geneV-D-J junctionSHM
BPT105 IGHV1-66*01 IGHD2-5*01 IGHJ4*01 GGGGGCTATAGTCAAATGAGGGGG 
BPT124 IGHV1S16*01 IGHD1-2*01 IGHJ2*01 GAGGGGATTACTACGGCTACC 
BPT137 IGHV1S127*01 IGHD4-1*02 IGHJ2*01 GACTGGGACGTCGG 
BPT234 IGHV1-47*01 IGHD2-4*01 IGHJ1*01 ATGATTACGACCACC 
Mouse ID*V geneD geneJ geneV-D-J junctionSHM
BPT105 IGHV1-66*01 IGHD2-5*01 IGHJ4*01 GGGGGCTATAGTCAAATGAGGGGG 
BPT124 IGHV1S16*01 IGHD1-2*01 IGHJ2*01 GAGGGGATTACTACGGCTACC 
BPT137 IGHV1S127*01 IGHD4-1*02 IGHJ2*01 GACTGGGACGTCGG 
BPT234 IGHV1-47*01 IGHD2-4*01 IGHJ1*01 ATGATTACGACCACC 

IGBLAST, immunoglobulin BLAST; IMGT international ImMunoGeneTics information system; NCBI, National Center for Biotechnology Information.

*

Mouse identification number.

Assignment of V, D, and J genes by NCBI/IGBLAST according to the IMGT database.

SHM.

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