Response vs patient characteristics and treatment
| . | Total . | Nonresponders, n (%) . | Responders, n (%) . | P value* . |
|---|---|---|---|---|
| N | 213 | 113 (53) | 100 (47) | |
| Treatment | ||||
| AZA alone | 42 (20) | 22 (52) | 20 (48) | .96 |
| DEC alone | 144 (68) | 76 (53) | 68 (47) | |
| DEC + Other | 27 (13) | 15 (56) | 12 (44) | |
| Sex | ||||
| Male | 155 (73) | 82 (53) | 73 (47) | .99 |
| Female | 58 (27) | 31 (53) | 27 (47) | |
| Age | ||||
| <70 y | 110 (52) | 64 (58) | 46 (42) | .13 |
| ≥70 y | 103 (48) | 49 (48) | 54 (52) | |
| FAB | ||||
| RA | 30 (14) | 20 (67) | 10 (33) | .008* |
| RARS | 24 (11) | 15 (63) | 9 (38) | |
| RAEB | 125 (59) | 65 (52) | 60 (48) | |
| RAEB-t | 6 (3) | 4 (67) | 2 (33) | |
| CMML | 21 (10) | 4 (19) | 17 (81) | |
| Other | 7 (3) | 5 (71) | 2 (29) | |
| IPSS risk group | ||||
| Low/Int-1 | 97 (46) | 53 (55) | 44 (45) | .78† |
| Int-2/High | 113 (53) | 59 (52) | 54 (48) | |
| Unknown | 3 (1) | 1 (33) | 2 (67) | |
| Cytogenetics | ||||
| Normal | 104 (49) | 49 (47) | 55 (53) | .31 |
| Complex | 51 (24) | 28 (55) | 23 (45) | |
| Other | 51 (24) | 31 (61) | 20 (39) | |
| Unknown | 7 (3) | 5 (71) | 2 (29) |
| . | Total . | Nonresponders, n (%) . | Responders, n (%) . | P value* . |
|---|---|---|---|---|
| N | 213 | 113 (53) | 100 (47) | |
| Treatment | ||||
| AZA alone | 42 (20) | 22 (52) | 20 (48) | .96 |
| DEC alone | 144 (68) | 76 (53) | 68 (47) | |
| DEC + Other | 27 (13) | 15 (56) | 12 (44) | |
| Sex | ||||
| Male | 155 (73) | 82 (53) | 73 (47) | .99 |
| Female | 58 (27) | 31 (53) | 27 (47) | |
| Age | ||||
| <70 y | 110 (52) | 64 (58) | 46 (42) | .13 |
| ≥70 y | 103 (48) | 49 (48) | 54 (52) | |
| FAB | ||||
| RA | 30 (14) | 20 (67) | 10 (33) | .008* |
| RARS | 24 (11) | 15 (63) | 9 (38) | |
| RAEB | 125 (59) | 65 (52) | 60 (48) | |
| RAEB-t | 6 (3) | 4 (67) | 2 (33) | |
| CMML | 21 (10) | 4 (19) | 17 (81) | |
| Other | 7 (3) | 5 (71) | 2 (29) | |
| IPSS risk group | ||||
| Low/Int-1 | 97 (46) | 53 (55) | 44 (45) | .78† |
| Int-2/High | 113 (53) | 59 (52) | 54 (48) | |
| Unknown | 3 (1) | 1 (33) | 2 (67) | |
| Cytogenetics | ||||
| Normal | 104 (49) | 49 (47) | 55 (53) | .31 |
| Complex | 51 (24) | 28 (55) | 23 (45) | |
| Other | 51 (24) | 31 (61) | 20 (39) | |
| Unknown | 7 (3) | 5 (71) | 2 (29) |