Table 1 SPMs in adult ALL SPM . N .... | American Society of Hematology

Table 1

SPMs in adult ALL

SPM	N	Expected	O/E	CI lower	CI upper	P	ER	Mean age at event, y
All sites	39	27.36	1.43*	1.01	1.95	.04	18.63	61.98
All sites excluding nonmelanoma skin	39	27.25	1.43*	1.02	1.96	.04	18.81	61.98
All solid tumors	30	24.31	1.23	0.83	1.76	.3	9.1	64.78
Oral cavity and pharynx	1	0.69	1.46	0.04	8.11	1	0.5	55.25
Digestive system	6	4.82	1.25	0.46	2.71	.7	1.89	77.38
Lung and bronchus	9	3.25	2.77*	1.27	5.26	.01	9.2	66.62
Breast	5	3.65	1.37	0.44	3.2	.6	2.16	66.52
Male genital system	2	5.3	0.38	0.05	1.36	.2	−5.29	63.13
Urinary system	5	2	2.51	0.81	5.85	.1	4.81	61.27
Brain and other nervous system	1	0.41	2.47	0.06	13.74	.6	0.95	33
Hematologic malignancies	8	2.44	3.28*	1.42	6.47	<.01	8.9	48.94
AML	6	0.21	28.48*	10.45	61.98	<.001	9.26	49.63

SPM	N	Expected	O/E	CI lower	CI upper	P	ER	Mean age at event, y
All sites	39	27.36	1.43*	1.01	1.95	.04	18.63	61.98
All sites excluding nonmelanoma skin	39	27.25	1.43*	1.02	1.96	.04	18.81	61.98
All solid tumors	30	24.31	1.23	0.83	1.76	.3	9.1	64.78
Oral cavity and pharynx	1	0.69	1.46	0.04	8.11	1	0.5	55.25
Digestive system	6	4.82	1.25	0.46	2.71	.7	1.89	77.38
Lung and bronchus	9	3.25	2.77*	1.27	5.26	.01	9.2	66.62
Breast	5	3.65	1.37	0.44	3.2	.6	2.16	66.52
Male genital system	2	5.3	0.38	0.05	1.36	.2	−5.29	63.13
Urinary system	5	2	2.51	0.81	5.85	.1	4.81	61.27
Brain and other nervous system	1	0.41	2.47	0.06	13.74	.6	0.95	33
Hematologic malignancies	8	2.44	3.28*	1.42	6.47	<.01	8.9	48.94
AML	6	0.21	28.48*	10.45	61.98	<.001	9.26	49.63

Totals: persons, 2168; PY, 6249.31; mean age at exposure, 41.66. CIs are 95%.

AML, acute myeloid leukemia; ER, excess risk per 10 000; N, observed number of SPMs.

P < .05.