Table 1

Table of 27 common genes differentially expressed in Runx1Δ/Δ and RUNX1SF HSPCs that overlap with RUNX1 genome occupancy

SymbolDescriptionRunx1Δ/Δ arrayRUNX1SF arrayPeak location
Adamtsl4 ADAMTS-like 4 2.42 3.37 chr3:95511225-95512034 
Alcam activated leukocyte cell adhesion molecule −2.05 −4.28 chr16:54016417-54016980 
Atp8a2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 2.05 2.84 chr14:60691216-60691929 
chr14:60748188-60748880 
Bdh1 3-hydroxybutyrate dehydrogenase, type 1 −2.35 −5.59 chr16:30967909-30969214 
chr16:30971738-30972608 
chr16:31080812-31081818 
chr16:31209726-31210547 
Cd72 CD72 antigen −2.08 −2.32 chr4:43469362-43470612 
Cpa3 carboxypeptidase A3 8.36 13.89 chr3:20141473-20142494 
chr3:20143698-20144216 
Csf2rb colony stimulating factor 2 receptor, β, low-affinity (granulocyte-macrophage) 2.41 2.74 chr15:78097680-78098791 
chr15:78150945-78151767 
Cyb561 cytochrome b561 −3.78 −3.34 chr11:105807879-105808525 
chr11:105820316-105821213 
chr11:105918137-105919089 
Deptor DEP domain containing MTOR-interacting protein 2.72 3.15 chr15:54963581-54964309 
chr15:55022569-55023361 
chr15:55049202-55050131 
Fhdc1 FH2 domain containing 1 3.48 4.5 chr3:84264390-84265426 
chr3:84295898-84296552 
chr3:84307981-84308734 
Fscn1 fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus−3.17 −32.73 chr5:143581961-143584992 
chr5:143656547-143657461 
chr5:143715033-143716206 
Gzmb granzyme B −3.94 −4.51 chr14:56880645-56881698 
chr14:56884808-56885570 
chr14:56914779-56915975 
chr14:56933192-56933620 
chr14:57190343-57191097 
Hmga2 high mobility group AT-hook 2 4.75 4.34 chr10:119760560-119761484 
chr10:119883733-119884448 
chr10:120053435-120054404 
Igf2r insulin-like growth factor 2 receptor −2.37 −10.81 chr17:12947269-12947943 
Itga2b integrin α 2b 2.5 4.19 chr11:102330569-102332184 
Itga9 integrin α 9 3.32 2.83 chr9:118541479-118542316 
chr9:118558410-118559222 
chr9:118625078-118626008 
chr9:118659770-118660359 
chr9:118792266-118792827 
Jam3 junction adhesion molecule 3 3.49 4.41 chr9:26906891-26907613 
Krt80 keratin 80 7.36 7.9 chr15:101218519-101219226 
Lcp2 lymphocyte cytosolic protein 2 2.12 2.16 chr11:33950589-33951437 
chr11:33963605-33964645 
chr11:33867349-338683 
chr11:33900230-33901036 
chr11:33909353-33911207 
Map3k6 mitogen-activated protein kinase kinase kinase 6 2.01 2.39 chr4:132793901-132794220 
Pcdh7 protocadherin 7 5.41 9.62 chr5:58108350-58109816 
chr5:58126695-58127555 
chr5:58232582-58233087 
chr5:58248528-58249096 
chr5:58422191-58422711 
Podxl podocalyxin-like 2.81 4.19 chr6:32107983-32109068 
Slc24a3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 4.95 7.09 chr2:145050905-145052230 
chr2:145087407-145088337 
Spp1 secreted phosphoprotein 1 −2.41 −3.6 chr5:104863923-104864409 
Stx3 syntaxin 3 2.66 3.32 chr19:11881628-11882355 
Tjp1 tight junction protein 1 6.45 6.76 chr7:72518004-72518826 
chr7:73323785-73326321 
chr7:73436915-73437490 
chr7:73448143-73449672 
Zcchc18 zinc finger, CCHC domain containing 18 −2.5 −10.84 chrX:133520640-133521165 
SymbolDescriptionRunx1Δ/Δ arrayRUNX1SF arrayPeak location
Adamtsl4 ADAMTS-like 4 2.42 3.37 chr3:95511225-95512034 
Alcam activated leukocyte cell adhesion molecule −2.05 −4.28 chr16:54016417-54016980 
Atp8a2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 2.05 2.84 chr14:60691216-60691929 
chr14:60748188-60748880 
Bdh1 3-hydroxybutyrate dehydrogenase, type 1 −2.35 −5.59 chr16:30967909-30969214 
chr16:30971738-30972608 
chr16:31080812-31081818 
chr16:31209726-31210547 
Cd72 CD72 antigen −2.08 −2.32 chr4:43469362-43470612 
Cpa3 carboxypeptidase A3 8.36 13.89 chr3:20141473-20142494 
chr3:20143698-20144216 
Csf2rb colony stimulating factor 2 receptor, β, low-affinity (granulocyte-macrophage) 2.41 2.74 chr15:78097680-78098791 
chr15:78150945-78151767 
Cyb561 cytochrome b561 −3.78 −3.34 chr11:105807879-105808525 
chr11:105820316-105821213 
chr11:105918137-105919089 
Deptor DEP domain containing MTOR-interacting protein 2.72 3.15 chr15:54963581-54964309 
chr15:55022569-55023361 
chr15:55049202-55050131 
Fhdc1 FH2 domain containing 1 3.48 4.5 chr3:84264390-84265426 
chr3:84295898-84296552 
chr3:84307981-84308734 
Fscn1 fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus−3.17 −32.73 chr5:143581961-143584992 
chr5:143656547-143657461 
chr5:143715033-143716206 
Gzmb granzyme B −3.94 −4.51 chr14:56880645-56881698 
chr14:56884808-56885570 
chr14:56914779-56915975 
chr14:56933192-56933620 
chr14:57190343-57191097 
Hmga2 high mobility group AT-hook 2 4.75 4.34 chr10:119760560-119761484 
chr10:119883733-119884448 
chr10:120053435-120054404 
Igf2r insulin-like growth factor 2 receptor −2.37 −10.81 chr17:12947269-12947943 
Itga2b integrin α 2b 2.5 4.19 chr11:102330569-102332184 
Itga9 integrin α 9 3.32 2.83 chr9:118541479-118542316 
chr9:118558410-118559222 
chr9:118625078-118626008 
chr9:118659770-118660359 
chr9:118792266-118792827 
Jam3 junction adhesion molecule 3 3.49 4.41 chr9:26906891-26907613 
Krt80 keratin 80 7.36 7.9 chr15:101218519-101219226 
Lcp2 lymphocyte cytosolic protein 2 2.12 2.16 chr11:33950589-33951437 
chr11:33963605-33964645 
chr11:33867349-338683 
chr11:33900230-33901036 
chr11:33909353-33911207 
Map3k6 mitogen-activated protein kinase kinase kinase 6 2.01 2.39 chr4:132793901-132794220 
Pcdh7 protocadherin 7 5.41 9.62 chr5:58108350-58109816 
chr5:58126695-58127555 
chr5:58232582-58233087 
chr5:58248528-58249096 
chr5:58422191-58422711 
Podxl podocalyxin-like 2.81 4.19 chr6:32107983-32109068 
Slc24a3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 4.95 7.09 chr2:145050905-145052230 
chr2:145087407-145088337 
Spp1 secreted phosphoprotein 1 −2.41 −3.6 chr5:104863923-104864409 
Stx3 syntaxin 3 2.66 3.32 chr19:11881628-11882355 
Tjp1 tight junction protein 1 6.45 6.76 chr7:72518004-72518826 
chr7:73323785-73326321 
chr7:73436915-73437490 
chr7:73448143-73449672 
Zcchc18 zinc finger, CCHC domain containing 18 −2.5 −10.84 chrX:133520640-133521165 
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