Table 1

Survival factors common to normal and myeloma plasma cells

Survival factorExamples
Membrane-bound factors (receptors) CD80/CD86 (CD28) 
Soluble factors (receptors) Interleukin-6 (IL6R), APRIL (BCMA), tumor necrosis factor α (TNFR) 
Intrinsic factors MCL1 
Survival factorExamples
Membrane-bound factors (receptors) CD80/CD86 (CD28) 
Soluble factors (receptors) Interleukin-6 (IL6R), APRIL (BCMA), tumor necrosis factor α (TNFR) 
Intrinsic factors MCL1 
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