Patient’s diagnosis and dose-level assignment
| Tumor diagnosis . | No. of patients at dose level (mg) . | All patients . | |||||
|---|---|---|---|---|---|---|---|
| 25 . | 75 . | 100 . | 125 . | 150 . | No. . | % . | |
| AML | 0 | 0 | 0 | 9 | 0 | 9 | 12.3 |
| ALL | 0 | 0 | 0 | 1 | 0 | 1 | 1.4 |
| CLL | 1 | 2 | 1 | 2 | 1 | 7 | 9.6 |
| HD | 1 | 0 | 2 | 4 | 1 | 8 | 11 |
| NHL | 0 | 0 | 3 | 7 | 3 | 13 | 17.8 |
| LCH | 0 | 0 | 0 | 0 | 1 | 1 | 1.4 |
| MM | 0 | 0 | 2 | 32 | 0 | 34 | 46.6 |
| Tumor diagnosis . | No. of patients at dose level (mg) . | All patients . | |||||
|---|---|---|---|---|---|---|---|
| 25 . | 75 . | 100 . | 125 . | 150 . | No. . | % . | |
| AML | 0 | 0 | 0 | 9 | 0 | 9 | 12.3 |
| ALL | 0 | 0 | 0 | 1 | 0 | 1 | 1.4 |
| CLL | 1 | 2 | 1 | 2 | 1 | 7 | 9.6 |
| HD | 1 | 0 | 2 | 4 | 1 | 8 | 11 |
| NHL | 0 | 0 | 3 | 7 | 3 | 13 | 17.8 |
| LCH | 0 | 0 | 0 | 0 | 1 | 1 | 1.4 |
| MM | 0 | 0 | 2 | 32 | 0 | 34 | 46.6 |