Table 1 Characteristics of patients and... | American Society of Hematology

Table 1

Characteristics of patients and donors

Characteristics	n = 92
Age in y, median (range) of the recipient	36 (18-54)
Gender, no.
Male	50
Female	42
WBCs at diagnosis ×10⁹/L, median (range)	9.6 (0.8-87)
c-KIT mutations, no.
Positive	33
Negative	48
Unknown	11
Karotype
Sole t(8;21)	51
Additional abnormalities other than t(8;21)	35
Complex karotype	6
Disease status
First CR (CR1)	86
Second CR (CR2)	6
Courses required to achieve CR
1	57
>1 (including CR2)	35
Time from diagnosis to transplant in mo, median (range)	6 (2.4-25)
Donor source
Haploidentical	44
HLA-matched sibling	43
Unrelated donor	5
Stem cell source
G-CSF mobilized BM + peripheral blood	75
G-CSF mobilized peripheral blood	17
Conditioning regimen
Chemotherapy based	88
TBI based	4
Median CD34⁺ count, ×10⁶/kg (range)	2.2 (0.4-5.5)
Median CD3⁺ count, ×10⁸/kg (range)	1.7 (0.3-8.4)

Characteristics	n = 92
Age in y, median (range) of the recipient	36 (18-54)
Gender, no.
Male	50
Female	42
WBCs at diagnosis ×10⁹/L, median (range)	9.6 (0.8-87)
c-KIT mutations, no.
Positive	33
Negative	48
Unknown	11
Karotype
Sole t(8;21)	51
Additional abnormalities other than t(8;21)	35
Complex karotype	6
Disease status
First CR (CR1)	86
Second CR (CR2)	6
Courses required to achieve CR
1	57
>1 (including CR2)	35
Time from diagnosis to transplant in mo, median (range)	6 (2.4-25)
Donor source
Haploidentical	44
HLA-matched sibling	43
Unrelated donor	5
Stem cell source
G-CSF mobilized BM + peripheral blood	75
G-CSF mobilized peripheral blood	17
Conditioning regimen
Chemotherapy based	88
TBI based	4
Median CD34⁺ count, ×10⁶/kg (range)	2.2 (0.4-5.5)
Median CD3⁺ count, ×10⁸/kg (range)	1.7 (0.3-8.4)

BM, bone marrow; G-CSF, granulocyte colony-stimulating factor; TBI, total body irradiation; WBC, white blood cell.