Characteristics of patients and donors
| Characteristics . | n = 92 . |
|---|---|
| Age in y, median (range) of the recipient | 36 (18-54) |
| Gender, no. | |
| Male | 50 |
| Female | 42 |
| WBCs at diagnosis ×109/L, median (range) | 9.6 (0.8-87) |
| c-KIT mutations, no. | |
| Positive | 33 |
| Negative | 48 |
| Unknown | 11 |
| Karotype | |
| Sole t(8;21) | 51 |
| Additional abnormalities other than t(8;21) | 35 |
| Complex karotype | 6 |
| Disease status | |
| First CR (CR1) | 86 |
| Second CR (CR2) | 6 |
| Courses required to achieve CR | |
| 1 | 57 |
| >1 (including CR2) | 35 |
| Time from diagnosis to transplant in mo, median (range) | 6 (2.4-25) |
| Donor source | |
| Haploidentical | 44 |
| HLA-matched sibling | 43 |
| Unrelated donor | 5 |
| Stem cell source | |
| G-CSF mobilized BM + peripheral blood | 75 |
| G-CSF mobilized peripheral blood | 17 |
| Conditioning regimen | |
| Chemotherapy based | 88 |
| TBI based | 4 |
| Median CD34+ count, ×106/kg (range) | 2.2 (0.4-5.5) |
| Median CD3+ count, ×108/kg (range) | 1.7 (0.3-8.4) |
| Characteristics . | n = 92 . |
|---|---|
| Age in y, median (range) of the recipient | 36 (18-54) |
| Gender, no. | |
| Male | 50 |
| Female | 42 |
| WBCs at diagnosis ×109/L, median (range) | 9.6 (0.8-87) |
| c-KIT mutations, no. | |
| Positive | 33 |
| Negative | 48 |
| Unknown | 11 |
| Karotype | |
| Sole t(8;21) | 51 |
| Additional abnormalities other than t(8;21) | 35 |
| Complex karotype | 6 |
| Disease status | |
| First CR (CR1) | 86 |
| Second CR (CR2) | 6 |
| Courses required to achieve CR | |
| 1 | 57 |
| >1 (including CR2) | 35 |
| Time from diagnosis to transplant in mo, median (range) | 6 (2.4-25) |
| Donor source | |
| Haploidentical | 44 |
| HLA-matched sibling | 43 |
| Unrelated donor | 5 |
| Stem cell source | |
| G-CSF mobilized BM + peripheral blood | 75 |
| G-CSF mobilized peripheral blood | 17 |
| Conditioning regimen | |
| Chemotherapy based | 88 |
| TBI based | 4 |
| Median CD34+ count, ×106/kg (range) | 2.2 (0.4-5.5) |
| Median CD3+ count, ×108/kg (range) | 1.7 (0.3-8.4) |
BM, bone marrow; G-CSF, granulocyte colony-stimulating factor; TBI, total body irradiation; WBC, white blood cell.