Erythropoietic response in the 2 arms
| . | MA rhEPO from D28 . | . | Non-MA rhEPO from D28 . | . | Non-MA rhEPO from D0 . | . | |||
|---|---|---|---|---|---|---|---|---|---|
| . | Control arm (N = 19) . | EPO arm (N = 15) . | P value . | Control arm (N = 18) . | EPO arm (N = 19) . | P value . | Control arm (N = 25) . | EPO arm (N = 23) . | P value . |
| Hb on the day of rhEPO initiation (mean ± SD) | 9.0 ± 1.3 | 8.8 ± 0.8 | NS | 9.6 ± 1.4 | 9.0 ± 1.1 | NS | 11.1 ± 1.9 | 10.1 ± 2.1 | NS |
| Time to Hb ≥13 g/dL | |||||||||
| % achieving (by D126 post-HCT) | 5.2 | 66.7 | 0 | 63.2 | 16.0 | 60.9 | |||
| Median (d) after starting rhEPO | Undefined | 116 | <.001 | Undefined | 52 | <.001 | Undefined | 91 | <.001 |
| Time to Hb + 2 g/dL | |||||||||
| % achieving (by D126 post-HCT) | 31.6 | 85.7 | 11.8 | 73.7 | 29.2 | 65.2 | |||
| Median (d) after starting rhEPO | 189 | 30 | <.001 | 307 | 33 | <.001 | Undefined | 72 | .020 |
| Time to Hb ≥12 g/dL | |||||||||
| % achieving (by D126 post-HCT) | 15.8 | 80.0 | 11.1 | 68.4 | 36.0 | 69.5 | |||
| Median (d) after starting rhEPO | Undefined | 47 | <.001 | Undefined | 38 | .001 | Undefined | 77 | .003 |
| . | MA rhEPO from D28 . | . | Non-MA rhEPO from D28 . | . | Non-MA rhEPO from D0 . | . | |||
|---|---|---|---|---|---|---|---|---|---|
| . | Control arm (N = 19) . | EPO arm (N = 15) . | P value . | Control arm (N = 18) . | EPO arm (N = 19) . | P value . | Control arm (N = 25) . | EPO arm (N = 23) . | P value . |
| Hb on the day of rhEPO initiation (mean ± SD) | 9.0 ± 1.3 | 8.8 ± 0.8 | NS | 9.6 ± 1.4 | 9.0 ± 1.1 | NS | 11.1 ± 1.9 | 10.1 ± 2.1 | NS |
| Time to Hb ≥13 g/dL | |||||||||
| % achieving (by D126 post-HCT) | 5.2 | 66.7 | 0 | 63.2 | 16.0 | 60.9 | |||
| Median (d) after starting rhEPO | Undefined | 116 | <.001 | Undefined | 52 | <.001 | Undefined | 91 | <.001 |
| Time to Hb + 2 g/dL | |||||||||
| % achieving (by D126 post-HCT) | 31.6 | 85.7 | 11.8 | 73.7 | 29.2 | 65.2 | |||
| Median (d) after starting rhEPO | 189 | 30 | <.001 | 307 | 33 | <.001 | Undefined | 72 | .020 |
| Time to Hb ≥12 g/dL | |||||||||
| % achieving (by D126 post-HCT) | 15.8 | 80.0 | 11.1 | 68.4 | 36.0 | 69.5 | |||
| Median (d) after starting rhEPO | Undefined | 47 | <.001 | Undefined | 38 | .001 | Undefined | 77 | .003 |
NS, not significant.