Table 2 Risk of bleeding in the 796 VWD... | American Society of Hematology

Table 2

Risk of bleeding in the 796 VWD patients according to clinical and laboratory predictors

	Crude HRs (95% CI)	Adjusted HRs (95% CI)*
BS
<5	1†	1†
5-10	2.10 (1.10-3.90)	2.05 (1.07-3.91)
>10	6.80 (3.80-12.30)	7.27 (3.83-13.83)
VWF:RCo, IU/dL
>30	1†	1†
10-30	1.51 (0.72-3.14)	1.16 (0.54-2.47)
<10	3.27 (1.77-6.06)	1.12 (0.50-2.51)
FVIII:C, IU/dL
>40	1†	1†
20-40	2.07 (1.16-3.69)	1.52 (0.80-2.90)
<20	4.20 (2.43-7.26)	2.20 (1.05-4.62)

	Crude HRs (95% CI)	Adjusted HRs (95% CI)*
BS
<5	1†	1†
5-10	2.10 (1.10-3.90)	2.05 (1.07-3.91)
>10	6.80 (3.80-12.30)	7.27 (3.83-13.83)
VWF:RCo, IU/dL
>30	1†	1†
10-30	1.51 (0.72-3.14)	1.16 (0.54-2.47)
<10	3.27 (1.77-6.06)	1.12 (0.50-2.51)
FVIII:C, IU/dL
>40	1†	1†
20-40	2.07 (1.16-3.69)	1.52 (0.80-2.90)
<20	4.20 (2.43-7.26)	2.20 (1.05-4.62)

The effect of each predictor on the bleeding risk was adjusted for that of the other ones, and for age and sex, in a multivariable Cox proportional hazard model.

†

Reference group.

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