Table 1
Grade of SOS
.
Mild
.
Moderate
.
Severe
.
Bilirubin, mg/dL
<5
5.1- 8
>8
Liver function
<3× normal
3-8× normal
>8× normal
Weight above baseline
<2%
2-5%
>5%
Renal function
Normal
<2× normal
>2× normal
Rate of change
Slow
Moderate
Rapid
.
Mild
.
Moderate
.
Severe
.
Bilirubin, mg/dL
<5
5.1- 8
>8
Liver function
<3× normal
3-8× normal
>8× normal
Weight above baseline
<2%
2-5%
>5%
Renal function
Normal
<2× normal
>2× normal
Rate of change
Slow
Moderate
Rapid
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