Table 1

Risk of bleeding in the 796 VWD patients according to clinical and laboratory predictors

Crude HRs (95% CI)Adjusted HRs (95% CI)*
BS   
 <5 1 1 
 5-10 2.10 (1.10-3.90) 2.05 (1.07-3.91) 
 >10 6.80 (3.80-12.30) 7.27 (3.83-13.83) 
VWF:RCo, IU/dL   
 >30 1 1 
 10-30 1.51 (0.72-3.14) 1.16 (0.54-2.47) 
 <10 3.27 (1.77-6.06) 1.12 (0.50-2.51) 
FVIII:C, IU/dL   
 >40 1 1 
 20-40 2.07 (1.16-3.69) 1.52 (0.80-2.90) 
 <20 4.20 (2.43-7.26) 2.20 (1.05-4.62) 
Crude HRs (95% CI)Adjusted HRs (95% CI)*
BS   
 <5 1 1 
 5-10 2.10 (1.10-3.90) 2.05 (1.07-3.91) 
 >10 6.80 (3.80-12.30) 7.27 (3.83-13.83) 
VWF:RCo, IU/dL   
 >30 1 1 
 10-30 1.51 (0.72-3.14) 1.16 (0.54-2.47) 
 <10 3.27 (1.77-6.06) 1.12 (0.50-2.51) 
FVIII:C, IU/dL   
 >40 1 1 
 20-40 2.07 (1.16-3.69) 1.52 (0.80-2.90) 
 <20 4.20 (2.43-7.26) 2.20 (1.05-4.62) 
*

The effect of each predictor on the bleeding risk was adjusted for that of the other ones and for age and sex, in a multivariable Cox proportional hazard model.

Reference group.

See Table 2 in the article by Federici et al beginning on page 4037.

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