Table 1

Demographic and clinical features of the 19 subjects clinically characterized as aHUS compared with a cohort of 38 patients with TTP with severely deficient ADAMTS13 activity

Median demographic and clinical data at presentation
Age (range)Sex (M/F)Race (AA/W)DialysisPlatelets (150-400 × 109)Creatinine (<1.1 mg/dL)LDH (<190 U/L)C3 (970-1576 mg/L)
aHUS patients (n = 19) 47 (20-69) 3/16 3/16 14/19 (74%) 46 (8-93) 4.39 (2.38-12.61) 1094 (140-3548) 915 (561-1550) 
TTP patients (n = 38) 42.5 (18-76) 12/26 8/30 0/38 12 (2-45) 1.15 (0.65-4.11) 966 (243-2449) ― 
Median demographic and clinical data at presentation
Age (range)Sex (M/F)Race (AA/W)DialysisPlatelets (150-400 × 109)Creatinine (<1.1 mg/dL)LDH (<190 U/L)C3 (970-1576 mg/L)
aHUS patients (n = 19) 47 (20-69) 3/16 3/16 14/19 (74%) 46 (8-93) 4.39 (2.38-12.61) 1094 (140-3548) 915 (561-1550) 
TTP patients (n = 38) 42.5 (18-76) 12/26 8/30 0/38 12 (2-45) 1.15 (0.65-4.11) 966 (243-2449) ― 

AA, African American; F, female; LDH, lactate dehydrogenase M, male; W, white.

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