Characteristics of first-time NMDP donors who donated a stem cell product between January 2004 and July 2009
Characteristic . | BM . | PBSC . | P . |
---|---|---|---|
N (%) . | N (%) . | ||
Number of donors | 2726 | 6768 | |
Number of donor centers | 81 | 76 | |
Number of collection centers | 83 | N/A | |
Number of apheresis centers | N/A | 98 | |
Donor sex | .168 | ||
Male | 1638 (60) | 4170 (62) | |
Female | 1088 (40) | 2598 (38) | |
Donor race/ethnicity | <.001 | ||
White | 1935 (71) | 5083 (75) | |
Hispanic | 294 (11) | 582 (9) | |
Black/African American | 165 (6) | 320 (5) | |
Asian/Pacific Islander | 144 (5) | 294 (4) | |
American Indian/Alaska Native | 42 (2) | 77 (1) | |
Other/multiple race | 130 (5) | 351 (5) | |
Decline/unknown | 16 (1) | 61 (1) | |
Donor age at donation, years | .100 | ||
18 to 30 | 973 (36) | 2380 (35) | |
31 to 40 | 878 (32) | 2202 (33) | |
41 to 50 | 684 (25) | 1616 (24) | |
51 to 61 | 191 (7) | 570 (8) | |
Median (range) | 35 (18-61) | 35 (18-61) | .377 |
Donor BMI, kg/m2 | .646 | ||
Underweight (<18.5) | 14 (1) | 41 (1) | |
Normal (18.5-24.9) | 825 (30) | 1970 (29) | |
Overweight (25-29.9) | 1044 (38) | 2659 (39) | |
Obese (≥30) | 843 (31) | 2097 (31) | |
Unknown | 0 | 1 (N/A) | |
Median (range) | 27.4 (16.1-50.9) | 27.4 (16.2-56.2) | .899 |
Donor cytomegalovirus | <.001 | ||
Nonreactive | 1554 (57) | 4124 (61) | |
Reactive | 1172 (43) | 2642 (39) | |
Unknown/indeterminate | 0 | 2 (N/A) | |
Donor white blood cell counts at baseline (×109/L) | |||
Median (range) | 6.4 (2.3-14.2) | 6.3 (2.3-16.0) | .544 |
Donor neutrophil counts at baseline (×109/L) | |||
Median (range) | 4.0 (1.0-12.5) | 4.0 (1.0-12.9) | .276 |
Donor mononuclear cell counts at baseline (×109/L) | |||
Median (range) | 2.3 (0.9-7.2) | 2.3 (0.3-7.3) | .633 |
Donor platelet counts at baseline (×109/L) | |||
Median (range) | 254 (104-534) | 254 (100-548) | .869 |
Donor hemoglobin level at baseline (g/dL) | |||
Male , median (range) | 15.3 (11.1-18.3) | 15.3 (10.9-19.0) | .800 |
Female, median (range) | 13.5 (8.6-19.0) | 13.4 (9.4-16.5) | .886 |
Year of donation | <.001 | ||
2004 | 491 (18) | 814 (12) | |
2005 | 449 (16) | 1102 (16) | |
2006 | 479 (18) | 1188 (18) | |
2007 | 471 (17) | 1297 (19) | |
2008 | 537 (20) | 1497 (22) | |
2009 | 299 (11) | 870 (13) |
Characteristic . | BM . | PBSC . | P . |
---|---|---|---|
N (%) . | N (%) . | ||
Number of donors | 2726 | 6768 | |
Number of donor centers | 81 | 76 | |
Number of collection centers | 83 | N/A | |
Number of apheresis centers | N/A | 98 | |
Donor sex | .168 | ||
Male | 1638 (60) | 4170 (62) | |
Female | 1088 (40) | 2598 (38) | |
Donor race/ethnicity | <.001 | ||
White | 1935 (71) | 5083 (75) | |
Hispanic | 294 (11) | 582 (9) | |
Black/African American | 165 (6) | 320 (5) | |
Asian/Pacific Islander | 144 (5) | 294 (4) | |
American Indian/Alaska Native | 42 (2) | 77 (1) | |
Other/multiple race | 130 (5) | 351 (5) | |
Decline/unknown | 16 (1) | 61 (1) | |
Donor age at donation, years | .100 | ||
18 to 30 | 973 (36) | 2380 (35) | |
31 to 40 | 878 (32) | 2202 (33) | |
41 to 50 | 684 (25) | 1616 (24) | |
51 to 61 | 191 (7) | 570 (8) | |
Median (range) | 35 (18-61) | 35 (18-61) | .377 |
Donor BMI, kg/m2 | .646 | ||
Underweight (<18.5) | 14 (1) | 41 (1) | |
Normal (18.5-24.9) | 825 (30) | 1970 (29) | |
Overweight (25-29.9) | 1044 (38) | 2659 (39) | |
Obese (≥30) | 843 (31) | 2097 (31) | |
Unknown | 0 | 1 (N/A) | |
Median (range) | 27.4 (16.1-50.9) | 27.4 (16.2-56.2) | .899 |
Donor cytomegalovirus | <.001 | ||
Nonreactive | 1554 (57) | 4124 (61) | |
Reactive | 1172 (43) | 2642 (39) | |
Unknown/indeterminate | 0 | 2 (N/A) | |
Donor white blood cell counts at baseline (×109/L) | |||
Median (range) | 6.4 (2.3-14.2) | 6.3 (2.3-16.0) | .544 |
Donor neutrophil counts at baseline (×109/L) | |||
Median (range) | 4.0 (1.0-12.5) | 4.0 (1.0-12.9) | .276 |
Donor mononuclear cell counts at baseline (×109/L) | |||
Median (range) | 2.3 (0.9-7.2) | 2.3 (0.3-7.3) | .633 |
Donor platelet counts at baseline (×109/L) | |||
Median (range) | 254 (104-534) | 254 (100-548) | .869 |
Donor hemoglobin level at baseline (g/dL) | |||
Male , median (range) | 15.3 (11.1-18.3) | 15.3 (10.9-19.0) | .800 |
Female, median (range) | 13.5 (8.6-19.0) | 13.4 (9.4-16.5) | .886 |
Year of donation | <.001 | ||
2004 | 491 (18) | 814 (12) | |
2005 | 449 (16) | 1102 (16) | |
2006 | 479 (18) | 1188 (18) | |
2007 | 471 (17) | 1297 (19) | |
2008 | 537 (20) | 1497 (22) | |
2009 | 299 (11) | 870 (13) |