Prevalence of thrombophilia at baseline
| . | Control group . | APS group . |
|---|---|---|
| Antiphospholipid antibodies aPLAb | ||
| LA | ||
| Positive for LA | 0 | 319 (61.7%) |
| Anticardiolipin IgG | ||
| Positive for aCL-G | 0 | 244 (47.2%) |
| aCL-G titer, µg/mL | 0.39 (0.21) [0.05-0.84] | 0.70 (1.37) [0.05-7.1] |
| Anticardiolipin IgM | ||
| Positive for aCL-M | 0 | 372 (71.9%) |
| aCL-M titer, µg/mL | 0.54 (0.32) [0.08-1.35] | 1.60 (1.55) [0.05-18.1] |
| Anti–β2-glycoprotein I IgG | ||
| Positive for aβ2GP1-G | 0 | 114 (22.1%) |
| aβ2GP1-G titer, µg/mL | 0.23 (0.14) [0.05-0.86] | 0.57 (0.55) [0.03-6.9] |
| Anti–β2-glycoprotein I IgM | ||
| Positive for aβ2GP1-M | 0 | 210 (40.6%) |
| aβ2GP1-M titer, µg/mL | 0.41 (0.24) [0.04-0.98] | 0.72 (0.85) [0.05-19.4] |
| Categories of positive aPLAb* | ||
| I | — | 383 (74.1%) |
| IIa | — | 31 (6%) |
| IIb | — | 103 (19.9%) |
| IIc | — | 0 |
| LA + aCL + aβ2GP1 | — | 149 (28.8%) |
| Constitutional thrombophilias | ||
| F5 rs6025 or F2 rs1799963 | 0 | 17 (3.3%) |
| . | Control group . | APS group . |
|---|---|---|
| Antiphospholipid antibodies aPLAb | ||
| LA | ||
| Positive for LA | 0 | 319 (61.7%) |
| Anticardiolipin IgG | ||
| Positive for aCL-G | 0 | 244 (47.2%) |
| aCL-G titer, µg/mL | 0.39 (0.21) [0.05-0.84] | 0.70 (1.37) [0.05-7.1] |
| Anticardiolipin IgM | ||
| Positive for aCL-M | 0 | 372 (71.9%) |
| aCL-M titer, µg/mL | 0.54 (0.32) [0.08-1.35] | 1.60 (1.55) [0.05-18.1] |
| Anti–β2-glycoprotein I IgG | ||
| Positive for aβ2GP1-G | 0 | 114 (22.1%) |
| aβ2GP1-G titer, µg/mL | 0.23 (0.14) [0.05-0.86] | 0.57 (0.55) [0.03-6.9] |
| Anti–β2-glycoprotein I IgM | ||
| Positive for aβ2GP1-M | 0 | 210 (40.6%) |
| aβ2GP1-M titer, µg/mL | 0.41 (0.24) [0.04-0.98] | 0.72 (0.85) [0.05-19.4] |
| Categories of positive aPLAb* | ||
| I | — | 383 (74.1%) |
| IIa | — | 31 (6%) |
| IIb | — | 103 (19.9%) |
| IIc | — | 0 |
| LA + aCL + aβ2GP1 | — | 149 (28.8%) |
| Constitutional thrombophilias | ||
| F5 rs6025 or F2 rs1799963 | 0 | 17 (3.3%) |
The control group comprised women negative for antiphospholipid antibodies. The APS group comprised women positive for antiphospholipid antibodies. Quantitative data are given as medians (interquartile range) [range], qualitative data as numbers (percentages).
Categories of positive aPLAb: type I, >1 laboratory criterion present; type IIa, LA present alone; type IIb, aCL-Ab present alone; and type IIc, aβ2GPI-Ab present alone.