Table 1 Associations between cluster and... | American Society of Hematology

Table 1

Associations between cluster and patient disease characteristics by MPN subtype

	P value§
	ET	PV	MF
Age	.01	.13	.78
Gender	.04	.02	.20
Language	<.001	<.001	.24
Risk score*	.43	.87	.001
MPN duration, y	.89	.73	.15
Laboratory abnormality	.04	.009	.79
Prior hemorrhage	.047	.06	.22
Prior thrombosis	.24	.12	.06
Prior splenectomy	.44	.43	.65
Spleen size†	.76	.002	.02
Palpable spleen	.75	.009	.009
Required red blood cell transfusion	.47	.63	.13
Receiving treatment‡	.21	.32	.64
Anemia, hemoglobin <11 g/dL	.01	.07	.48
Leukopenia, leukocyte count <3.5 × 10⁹/L	.14	.01	.009
Thrombocytopenia, platelet count <150 × 10⁹/L	.28	.31	<.001

	P value§
	ET	PV	MF
Age	.01	.13	.78
Gender	.04	.02	.20
Language	<.001	<.001	.24
Risk score*	.43	.87	.001
MPN duration, y	.89	.73	.15
Laboratory abnormality	.04	.009	.79
Prior hemorrhage	.047	.06	.22
Prior thrombosis	.24	.12	.06
Prior splenectomy	.44	.43	.65
Spleen size†	.76	.002	.02
Palpable spleen	.75	.009	.009
Required red blood cell transfusion	.47	.63	.13
Receiving treatment‡	.21	.32	.64
Anemia, hemoglobin <11 g/dL	.01	.07	.48
Leukopenia, leukocyte count <3.5 × 10⁹/L	.14	.01	.009
Thrombocytopenia, platelet count <150 × 10⁹/L	.28	.31	<.001

Risk scores as assessed by IPSET¹⁰ (ET), Tefferi et al (2012)⁹ (PV), or DIPSS⁸ (MF).

Spleen size determined by physical examination, with the mean size being represented by the number of centimeters below the left costal margin.

Treatment vs no treatment/aspirin only.

See supplemental Tables A1-3 for point estimates and measures of variability for each stated P value.