Table 2

Type of histological approach and diagnostic FDG/PET (n = 332)

CLL histology
HIC (n = 120)HAC (n = 117)RS (n = 95)
No.%No.%No.%
Tissue diagnosis   
 Core/excisional biopsy 58 48 53 45 38 40 
 FNA 27 23 43 37 25 26 
 Both procedures 35 29 21 18 32 34 
  Diagnostic FNA 27 77 15 71 15 47 
  ND FNA* 8 23 6 29 17 53 
FDG/PET†       
 SUVmax       
  Median 3.7 6.8 17.6 
  Range (0-14.3) (0-37.8) (0-56.3) 
 SUVmax ≥5 41 34 84 72 84 88 
 PET-ex disease 17 14 45 38 57 60 
CLL histology
HIC (n = 120)HAC (n = 117)RS (n = 95)
No.%No.%No.%
Tissue diagnosis   
 Core/excisional biopsy 58 48 53 45 38 40 
 FNA 27 23 43 37 25 26 
 Both procedures 35 29 21 18 32 34 
  Diagnostic FNA 27 77 15 71 15 47 
  ND FNA* 8 23 6 29 17 53 
FDG/PET†       
 SUVmax       
  Median 3.7 6.8 17.6 
  Range (0-14.3) (0-37.8) (0-56.3) 
 SUVmax ≥5 41 34 84 72 84 88 
 PET-ex disease 17 14 45 38 57 60 

ND, nondiagnostic.

*

Includes absence of malignant cells in tissue specimen or histologic downgrading in FNA compared with core or excisional biopsy.

†

P value for comparisons of SUVmax, SUVmax ≥5, and PET-ex disease <.0001.

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