Table 2

Antibodies against cell surface or synaptic antigens

AntibodySyndromeCancer
NMDAR Encephalitis Ovarian teratoma (rare in children, present in 58% older than 18 y) 
LGI1 LE None 
VGCC LEMS SCLC (50%)10  
GABABLE SCLC (70%)11  
CASPR2 Morvan syndrome Thymoma (38%)12  
AMPAR LE SCLC, breast, thymus (60%)13  
DPPX Encephalitis None14  
mGluR1 Cerebellar ataxia A few cases reported, two with HL15  
mGluR5 LE HL (only two cases reported)16  
AntibodySyndromeCancer
NMDAR Encephalitis Ovarian teratoma (rare in children, present in 58% older than 18 y) 
LGI1 LE None 
VGCC LEMS SCLC (50%)10  
GABABLE SCLC (70%)11  
CASPR2 Morvan syndrome Thymoma (38%)12  
AMPAR LE SCLC, breast, thymus (60%)13  
DPPX Encephalitis None14  
mGluR1 Cerebellar ataxia A few cases reported, two with HL15  
mGluR5 LE HL (only two cases reported)16  

AMPAR, AMPA receptor; CASPR2, contactin-associated protein 2; DPPX, dipeptidyl-peptidase-like protein-6; GABABR, GABAB receptor; LGI1, leucine-rich, glioma inactivated 1 protein; NMDAR, N-methyl-d-aspartate receptor; SCLC, small-cell lung cancer; VGCC, voltage-gated calcium channel.

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