Antibodies against cell surface or synaptic antigens
Antibody . | Syndrome . | Cancer . |
---|---|---|
NMDAR | Encephalitis | Ovarian teratoma (rare in children, present in 58% older than 18 y)8 |
LGI1 | LE | None9 |
VGCC | LEMS | SCLC (50%)10 |
GABABR | LE | SCLC (70%)11 |
CASPR2 | Morvan syndrome | Thymoma (38%)12 |
AMPAR | LE | SCLC, breast, thymus (60%)13 |
DPPX | Encephalitis | None14 |
mGluR1 | Cerebellar ataxia | A few cases reported, two with HL15 |
mGluR5 | LE | HL (only two cases reported)16 |
Antibody . | Syndrome . | Cancer . |
---|---|---|
NMDAR | Encephalitis | Ovarian teratoma (rare in children, present in 58% older than 18 y)8 |
LGI1 | LE | None9 |
VGCC | LEMS | SCLC (50%)10 |
GABABR | LE | SCLC (70%)11 |
CASPR2 | Morvan syndrome | Thymoma (38%)12 |
AMPAR | LE | SCLC, breast, thymus (60%)13 |
DPPX | Encephalitis | None14 |
mGluR1 | Cerebellar ataxia | A few cases reported, two with HL15 |
mGluR5 | LE | HL (only two cases reported)16 |
AMPAR, AMPA receptor; CASPR2, contactin-associated protein 2; DPPX, dipeptidyl-peptidase-like protein-6; GABABR, GABAB receptor; LGI1, leucine-rich, glioma inactivated 1 protein; NMDAR, N-methyl-d-aspartate receptor; SCLC, small-cell lung cancer; VGCC, voltage-gated calcium channel.