List of top 50 genes down-regulated by IL-4 in resident macrophages
| Gene symbol . | Name . | Fold change . |
|---|---|---|
| Cxcl13 | Chemokine (C-X-C motif) ligand 13 | 0.0020 |
| Lyz2 | Lysozyme 2 | 0.0081 |
| Atf7 | Activating transcription factor 7 | 0.0131 |
| Lpl | Lipoprotein lipase | 0.0177 |
| Irf8 | Interferon regulatory factor 8 | 0.0192 |
| Apoc2 | Apolipoprotein C-II | 0.0196 |
| Dusp6 | Dual specificity phosphatase 6 | 0.0219 |
| Clec7a | C-type lectin domain family 7, member a | 0.0238 |
| Apoc1 | Apolipoprotein C-I | 0.0300 |
| Hp | Haptoglobin | 0.0339 |
| Gm1673 | Predicted gene 1673 | 0.0344 |
| Gm11538 | Predicted gene 11538 | 0.0367 |
| Fcgr1 | Fc receptor, IgG, high affinity I | 0.0375 |
| Pltp | Phospholipid transfer protein | 0.0386 |
| Ccl3 | Chemokine (C-C motif) ligand 3 | 0.0439 |
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0441 |
| Hspa1a | Heat shock protein 1A | 0.0494 |
| Rgs2 | Regulator of G-protein signaling 2 | 0.0526 |
| Lama3 | Laminin, α 3 | 0.0563 |
| Nat8l | N-acetyltransferase 8-like | 0.0564 |
| Apoc4 | Apolipoprotein C-IV | 0.0644 |
| Clec4d | C-type lectin domain family 4, member d | 0.0673 |
| Rab6b | RAB6B, member RAS oncogene family | 0.0704 |
| Emb | Embigin | 0.0707 |
| F13a1 | Coagulation factor XIII, A1 subunit | 0.0713 |
| Fpr1 | Formyl peptide receptor 1 | 0.0714 |
| Upk1a | Uroplakin 1A | 0.0718 |
| Cd63 | CD63 antigen | 0.0744 |
| Gm4788 | Predicted gene 4788 | 0.0773 |
| Ccm2l | Cerebral cavernous malformation 2-like | 0.0782 |
| Marco | Macrophage receptor with collagenous structure | 0.0804 |
| Fpr2 | Formyl peptide receptor 2 | 0.0805 |
| Fkbp1a | FK506 binding protein 1a | 0.0805 |
| 1700003F12Rik | RIKEN cDNA 1700003F12 gene | 0.0806 |
| Apoe | Apolipoprotein E | 0.0850 |
| Rprm | Reprimo, TP53 dependent G2 arrest mediator candidate | 0.0854 |
| Cfhr2 | Complement factor H-related 2 | 0.0855 |
| Abca9 | ATP-binding cassette, sub-family A (ABC1), member 9 | 0.0913 |
| Cfh | Complement component factor h | 0.0924 |
| Egfl7 | EGF-like domain 7 | 0.0930 |
| Olfr871 | Olfactory receptor 871 | 0.0934 |
| Neurl3 | Neuralized homolog 3 homolog (Drosophila) | 0.0949 |
| Rgs1 | Regulator of G-protein signaling 1 | 0.0949 |
| Rs5-8s1 | Unknown | 0.0977 |
| Prom1 | Prominin 1 | 0.0986 |
| Ldhb | Lactate dehydrogenase B | 0.0987 |
| Rhbdf1 | Rhomboid family 1 (Drosophila) | 0.1027 |
| Fut7 | Fucosyltransferase 7 | 0.1038 |
| Pilra | Paired immunoglobin-like type 2 receptor α | 0.1082 |
| Lst1 | Leukocyte specific transcript 1 | 0.1086 |
| Gene symbol . | Name . | Fold change . |
|---|---|---|
| Cxcl13 | Chemokine (C-X-C motif) ligand 13 | 0.0020 |
| Lyz2 | Lysozyme 2 | 0.0081 |
| Atf7 | Activating transcription factor 7 | 0.0131 |
| Lpl | Lipoprotein lipase | 0.0177 |
| Irf8 | Interferon regulatory factor 8 | 0.0192 |
| Apoc2 | Apolipoprotein C-II | 0.0196 |
| Dusp6 | Dual specificity phosphatase 6 | 0.0219 |
| Clec7a | C-type lectin domain family 7, member a | 0.0238 |
| Apoc1 | Apolipoprotein C-I | 0.0300 |
| Hp | Haptoglobin | 0.0339 |
| Gm1673 | Predicted gene 1673 | 0.0344 |
| Gm11538 | Predicted gene 11538 | 0.0367 |
| Fcgr1 | Fc receptor, IgG, high affinity I | 0.0375 |
| Pltp | Phospholipid transfer protein | 0.0386 |
| Ccl3 | Chemokine (C-C motif) ligand 3 | 0.0439 |
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0441 |
| Hspa1a | Heat shock protein 1A | 0.0494 |
| Rgs2 | Regulator of G-protein signaling 2 | 0.0526 |
| Lama3 | Laminin, α 3 | 0.0563 |
| Nat8l | N-acetyltransferase 8-like | 0.0564 |
| Apoc4 | Apolipoprotein C-IV | 0.0644 |
| Clec4d | C-type lectin domain family 4, member d | 0.0673 |
| Rab6b | RAB6B, member RAS oncogene family | 0.0704 |
| Emb | Embigin | 0.0707 |
| F13a1 | Coagulation factor XIII, A1 subunit | 0.0713 |
| Fpr1 | Formyl peptide receptor 1 | 0.0714 |
| Upk1a | Uroplakin 1A | 0.0718 |
| Cd63 | CD63 antigen | 0.0744 |
| Gm4788 | Predicted gene 4788 | 0.0773 |
| Ccm2l | Cerebral cavernous malformation 2-like | 0.0782 |
| Marco | Macrophage receptor with collagenous structure | 0.0804 |
| Fpr2 | Formyl peptide receptor 2 | 0.0805 |
| Fkbp1a | FK506 binding protein 1a | 0.0805 |
| 1700003F12Rik | RIKEN cDNA 1700003F12 gene | 0.0806 |
| Apoe | Apolipoprotein E | 0.0850 |
| Rprm | Reprimo, TP53 dependent G2 arrest mediator candidate | 0.0854 |
| Cfhr2 | Complement factor H-related 2 | 0.0855 |
| Abca9 | ATP-binding cassette, sub-family A (ABC1), member 9 | 0.0913 |
| Cfh | Complement component factor h | 0.0924 |
| Egfl7 | EGF-like domain 7 | 0.0930 |
| Olfr871 | Olfactory receptor 871 | 0.0934 |
| Neurl3 | Neuralized homolog 3 homolog (Drosophila) | 0.0949 |
| Rgs1 | Regulator of G-protein signaling 1 | 0.0949 |
| Rs5-8s1 | Unknown | 0.0977 |
| Prom1 | Prominin 1 | 0.0986 |
| Ldhb | Lactate dehydrogenase B | 0.0987 |
| Rhbdf1 | Rhomboid family 1 (Drosophila) | 0.1027 |
| Fut7 | Fucosyltransferase 7 | 0.1038 |
| Pilra | Paired immunoglobin-like type 2 receptor α | 0.1082 |
| Lst1 | Leukocyte specific transcript 1 | 0.1086 |