List of 50 genes regulated by IL-4 in both resident and monocyte-derived macrophages
| Gene symbol . | Description . | Fold change* . |
|---|---|---|
| AA467197 | Expressed sequence AA467197 | 367.4197 |
| Chi3l4 | Chitinase-like 4 or Ym2 | 310.8889 |
| Aqp3 | Aquaporin 3 | 156.1061 |
| Ddx4 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 | 127.3663 |
| Ear11 | Eosinophil-associated, ribonuclease A family, member 11 | 96.4100 |
| Ear10 | Eosinophil-associated, ribonuclease A family, member 10 | 88.2232 |
| Cst7 | Cystatin F (leukocystatin) | 86.1656 |
| Tuba8 | Tubulin, α 8 | 58.8395 |
| Ear12 | Eosinophil-associated, ribonuclease A family, member 12 | 46.9911 |
| Asns | Asparagine synthetase | 46.9515 |
| Chi3l3 | Chitinase-like 3 or Ym1 | 44.8807 |
| Cdh1 | Cadherin 1 | 44.7643 |
| Cish | Cytokine inducible SH2-containing protein | 33.5730 |
| Gm4610 | Predicted gene 4610 | 28.9111 |
| Gm6756 | Predicted gene 6756 | 28.5975 |
| Gfra2 | Glial cell line derived neurotrophic factor family receptor α 2 | 28.3951 |
| Phgdh | 3-Phosphoglycerate dehydrogenase | 28.1069 |
| Slc7a2 | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 27.6141 |
| Gm5150 | Predicted gene 5150 | 26.6933 |
| A530064D06Rik | RIKEN cDNA A530064D06 gene | 26.5447 |
| Ear2 | Eosinophil-associated, ribonuclease A family, member 2 | 25.9995 |
| Gatm | Glycine amidinotransferase (l-arginine:glycine amidinotransferase) | 25.6794 |
| Pi16 | Peptidase inhibitor 16 | 23.3797 |
| Flt1 | FMS-like tyrosine kinase 1 | 23.0790 |
| Fbp1 | Fructose bisphosphatase 1 | 22.4783 |
| Apoe | Apolipoprotein E | 0.0499 |
| Clec4d | C-type lectin domain family 4, member d | 0.0532 |
| Apoc2 | Apolipoprotein C-II | 0.0551 |
| Atf7 | Activating transcription factor 7 | 0.0663 |
| Irf8 | Interferon regulatory factor 8 | 0.0682 |
| Gm11538 | Predicted gene 11538 | 0.0778 |
| Fcgr1 | Fc receptor, IgG, high affinity I | 0.0858 |
| Rgs1 | Regulator of G-protein signaling 1 | 0.0877 |
| Ccl3 | Chemokine (C-C motif) ligand 3 | 0.0880 |
| Prom1 | Prominin 1 | 0.0982 |
| Gm1673 | Predicted gene 1673 | 0.1016 |
| Cdkn1c | Cyclin-dependent kinase inhibitor 1C (P57) | 0.1045 |
| Olfr871 | Olfactory receptor 871 | 0.1055 |
| Neurl3 | Neuralized homolog 3 homolog (Drosophila) | 0.1063 |
| Lyz2 | Lysozyme 2 | 0.1138 |
| Itgb5 | Integrin β 5 | 0.1160 |
| Lst1 | Leukocyte specific transcript 1 | 0.1253 |
| Rnf150 | Ring finger protein 150 | 0.1274 |
| Itga6 | Integrin α 6 | 0.1277 |
| Cnrip1 | Cannabinoid receptor interacting protein 1 | 0.1286 |
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.1294 |
| Cbr2 | Carbonyl reductase 2 | 0.1316 |
| 1700003F12Rik | RIKEN cDNA 1700003F12 gene | 0.1339 |
| Lmo2 | LIM domain only 2 | 0.1416 |
| Ldhb | Lactate dehydrogenase B | 0.1431 |
| Gene symbol . | Description . | Fold change* . |
|---|---|---|
| AA467197 | Expressed sequence AA467197 | 367.4197 |
| Chi3l4 | Chitinase-like 4 or Ym2 | 310.8889 |
| Aqp3 | Aquaporin 3 | 156.1061 |
| Ddx4 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 | 127.3663 |
| Ear11 | Eosinophil-associated, ribonuclease A family, member 11 | 96.4100 |
| Ear10 | Eosinophil-associated, ribonuclease A family, member 10 | 88.2232 |
| Cst7 | Cystatin F (leukocystatin) | 86.1656 |
| Tuba8 | Tubulin, α 8 | 58.8395 |
| Ear12 | Eosinophil-associated, ribonuclease A family, member 12 | 46.9911 |
| Asns | Asparagine synthetase | 46.9515 |
| Chi3l3 | Chitinase-like 3 or Ym1 | 44.8807 |
| Cdh1 | Cadherin 1 | 44.7643 |
| Cish | Cytokine inducible SH2-containing protein | 33.5730 |
| Gm4610 | Predicted gene 4610 | 28.9111 |
| Gm6756 | Predicted gene 6756 | 28.5975 |
| Gfra2 | Glial cell line derived neurotrophic factor family receptor α 2 | 28.3951 |
| Phgdh | 3-Phosphoglycerate dehydrogenase | 28.1069 |
| Slc7a2 | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 27.6141 |
| Gm5150 | Predicted gene 5150 | 26.6933 |
| A530064D06Rik | RIKEN cDNA A530064D06 gene | 26.5447 |
| Ear2 | Eosinophil-associated, ribonuclease A family, member 2 | 25.9995 |
| Gatm | Glycine amidinotransferase (l-arginine:glycine amidinotransferase) | 25.6794 |
| Pi16 | Peptidase inhibitor 16 | 23.3797 |
| Flt1 | FMS-like tyrosine kinase 1 | 23.0790 |
| Fbp1 | Fructose bisphosphatase 1 | 22.4783 |
| Apoe | Apolipoprotein E | 0.0499 |
| Clec4d | C-type lectin domain family 4, member d | 0.0532 |
| Apoc2 | Apolipoprotein C-II | 0.0551 |
| Atf7 | Activating transcription factor 7 | 0.0663 |
| Irf8 | Interferon regulatory factor 8 | 0.0682 |
| Gm11538 | Predicted gene 11538 | 0.0778 |
| Fcgr1 | Fc receptor, IgG, high affinity I | 0.0858 |
| Rgs1 | Regulator of G-protein signaling 1 | 0.0877 |
| Ccl3 | Chemokine (C-C motif) ligand 3 | 0.0880 |
| Prom1 | Prominin 1 | 0.0982 |
| Gm1673 | Predicted gene 1673 | 0.1016 |
| Cdkn1c | Cyclin-dependent kinase inhibitor 1C (P57) | 0.1045 |
| Olfr871 | Olfactory receptor 871 | 0.1055 |
| Neurl3 | Neuralized homolog 3 homolog (Drosophila) | 0.1063 |
| Lyz2 | Lysozyme 2 | 0.1138 |
| Itgb5 | Integrin β 5 | 0.1160 |
| Lst1 | Leukocyte specific transcript 1 | 0.1253 |
| Rnf150 | Ring finger protein 150 | 0.1274 |
| Itga6 | Integrin α 6 | 0.1277 |
| Cnrip1 | Cannabinoid receptor interacting protein 1 | 0.1286 |
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.1294 |
| Cbr2 | Carbonyl reductase 2 | 0.1316 |
| 1700003F12Rik | RIKEN cDNA 1700003F12 gene | 0.1339 |
| Lmo2 | LIM domain only 2 | 0.1416 |
| Ldhb | Lactate dehydrogenase B | 0.1431 |
Calculated as average fold change of genes regulated by IL-4 in resident macrophage and genes regulated by IL-4 in monocyte-derived macrophages.