List of top 50 genes up-regulated by IL-4 in monocyte-derived macrophages
| Gene symbol . | Description . | Fold change . |
|---|---|---|
| Ccl24 | Chemokine (C-C motif) ligand 24 | 308.1040 |
| Ddx4 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 | 147.2503 |
| Ear11 | Eosinophil-associated, ribonuclease A family, member 11 | 129.8195 |
| Tuba8 | Tubulin, α 8 | 114.0360 |
| Ear10 | Eosinophil-associated, ribonuclease A family, member 10 | 109.5308 |
| Chi3l4 | Chitinase-like 4 or Ym2 | 95.2618 |
| Ear1 | Eosinophil-associated, ribonuclease A family, member 1 | 90.4369 |
| Ear12 | Eosinophil-associated, ribonuclease A family, member 12 | 88.9709 |
| Cdh1 | Cadherin 1 | 73.2850 |
| Il4i1 | Interleukin 4 induced 1 | 71.5692 |
| AA467197 | Expressed sequence AA467197 | 68.8517 |
| Asns | Asparagine synthetase | 60.0067 |
| Ch25h | Cholesterol 25-hydroxylase | 59.7103 |
| Cish | Cytokine inducible SH2-containing protein | 59.3660 |
| Gm6756 | Predicted gene 6756 | 53.0013 |
| Ear2 | Eosinophil-associated, ribonuclease A family, member 2 | 47.4012 |
| Vdr | Vitamin D receptor | 42.3885 |
| Timp1 | Tissue inhibitor of metalloproteinase 1 | 40.8995 |
| Pi16 | Peptidase inhibitor 16 | 39.9049 |
| Fbp1 | Fructose bisphosphatase 1 | 37.6432 |
| Cst7 | Cystatin F (leukocystatin) | 36.9475 |
| Klk8 | Kallikrein related-peptidase 8 | 36.9350 |
| Gfra2 | Glial cell line derived neurotrophic factor family receptor α 2 | 36.3341 |
| Phgdh | 3-phosphoglycerate dehydrogenase | 36.1081 |
| Tarm1 | T cell-interacting, activating receptor on myeloid cells 1 | 36.1055 |
| Ramp3 | Receptor (calcitonin) activity modifying protein 3 | 31.2576 |
| A530064D06Rik | RIKEN cDNA A530064D06 gene | 26.3184 |
| Slc7a2 | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 24.4996 |
| Msx3 | msh homeobox 3 | 21.9209 |
| Nlrp1a | NLR family, pyrin domain containing 1A | 21.6752 |
| Ccl7 | Chemokine (C-C motif) ligand 7 | 21.4119 |
| Car6 | Carbonic anhydrase 6 | 20.7420 |
| Cebpe | CCAAT/enhancer binding protein (C/EBP), ε | 20.2090 |
| Aldh1a2 | Aldehyde dehydrogenase family 1, subfamily A2 | 19.2205 |
| Ccl17 | Chemokine (C-C motif) ligand 17 | 19.2074 |
| Mthfd2 | Methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase | 16.9681 |
| Aqp3 | Aquaporin 3 | 16.4622 |
| Alox15 | Arachidonate 15-lipoxygenase | 15.4346 |
| Retnla | Resistin like α | 15.3394 |
| Ltb4r1 | Leukotriene B4 receptor 1 | 15.2231 |
| Retnlg | Resistin like γ | 15.1644 |
| Flt1 | FMS-like tyrosine kinase 1 | 14.4730 |
| Olr1 | Oxidized low density lipoprotein (lectin-like) receptor 1 | 14.4345 |
| Cd81 | CD81 antigen | 14.2763 |
| Slc7a5 | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 13.8395 |
| Fcrls | Fc receptor-like S, scavenger receptor | 12.9906 |
| Ap4e1 | Adaptor-related protein complex AP-4, ε 1 | 12.5573 |
| Hic1 | Hypermethylated in cancer 1 | 12.2985 |
| Rnase6 | Ribonuclease, RNase A family, 6 | 12.1713 |
| Slc30a4 | Solute carrier family 30 (zinc transporter), member 4 | 12.0286 |
| Gene symbol . | Description . | Fold change . |
|---|---|---|
| Ccl24 | Chemokine (C-C motif) ligand 24 | 308.1040 |
| Ddx4 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 | 147.2503 |
| Ear11 | Eosinophil-associated, ribonuclease A family, member 11 | 129.8195 |
| Tuba8 | Tubulin, α 8 | 114.0360 |
| Ear10 | Eosinophil-associated, ribonuclease A family, member 10 | 109.5308 |
| Chi3l4 | Chitinase-like 4 or Ym2 | 95.2618 |
| Ear1 | Eosinophil-associated, ribonuclease A family, member 1 | 90.4369 |
| Ear12 | Eosinophil-associated, ribonuclease A family, member 12 | 88.9709 |
| Cdh1 | Cadherin 1 | 73.2850 |
| Il4i1 | Interleukin 4 induced 1 | 71.5692 |
| AA467197 | Expressed sequence AA467197 | 68.8517 |
| Asns | Asparagine synthetase | 60.0067 |
| Ch25h | Cholesterol 25-hydroxylase | 59.7103 |
| Cish | Cytokine inducible SH2-containing protein | 59.3660 |
| Gm6756 | Predicted gene 6756 | 53.0013 |
| Ear2 | Eosinophil-associated, ribonuclease A family, member 2 | 47.4012 |
| Vdr | Vitamin D receptor | 42.3885 |
| Timp1 | Tissue inhibitor of metalloproteinase 1 | 40.8995 |
| Pi16 | Peptidase inhibitor 16 | 39.9049 |
| Fbp1 | Fructose bisphosphatase 1 | 37.6432 |
| Cst7 | Cystatin F (leukocystatin) | 36.9475 |
| Klk8 | Kallikrein related-peptidase 8 | 36.9350 |
| Gfra2 | Glial cell line derived neurotrophic factor family receptor α 2 | 36.3341 |
| Phgdh | 3-phosphoglycerate dehydrogenase | 36.1081 |
| Tarm1 | T cell-interacting, activating receptor on myeloid cells 1 | 36.1055 |
| Ramp3 | Receptor (calcitonin) activity modifying protein 3 | 31.2576 |
| A530064D06Rik | RIKEN cDNA A530064D06 gene | 26.3184 |
| Slc7a2 | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 24.4996 |
| Msx3 | msh homeobox 3 | 21.9209 |
| Nlrp1a | NLR family, pyrin domain containing 1A | 21.6752 |
| Ccl7 | Chemokine (C-C motif) ligand 7 | 21.4119 |
| Car6 | Carbonic anhydrase 6 | 20.7420 |
| Cebpe | CCAAT/enhancer binding protein (C/EBP), ε | 20.2090 |
| Aldh1a2 | Aldehyde dehydrogenase family 1, subfamily A2 | 19.2205 |
| Ccl17 | Chemokine (C-C motif) ligand 17 | 19.2074 |
| Mthfd2 | Methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase | 16.9681 |
| Aqp3 | Aquaporin 3 | 16.4622 |
| Alox15 | Arachidonate 15-lipoxygenase | 15.4346 |
| Retnla | Resistin like α | 15.3394 |
| Ltb4r1 | Leukotriene B4 receptor 1 | 15.2231 |
| Retnlg | Resistin like γ | 15.1644 |
| Flt1 | FMS-like tyrosine kinase 1 | 14.4730 |
| Olr1 | Oxidized low density lipoprotein (lectin-like) receptor 1 | 14.4345 |
| Cd81 | CD81 antigen | 14.2763 |
| Slc7a5 | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 13.8395 |
| Fcrls | Fc receptor-like S, scavenger receptor | 12.9906 |
| Ap4e1 | Adaptor-related protein complex AP-4, ε 1 | 12.5573 |
| Hic1 | Hypermethylated in cancer 1 | 12.2985 |
| Rnase6 | Ribonuclease, RNase A family, 6 | 12.1713 |
| Slc30a4 | Solute carrier family 30 (zinc transporter), member 4 | 12.0286 |