Table 1 Summary of MDS PBMC population... | American Society of Hematology

Table 1

Summary of MDS PBMC population frequencies

	Normal (n = 20)	MDS (n = 67)	P value
CD45⁺/SSC^lo (nonmyeloid)*	74% ± 2%	50% ± 2%	<.0001
CD45⁺/CD7⁺ lymphocytes*	54% ± 3%	25% ± 2%	<.0001
CD56⁺/CD3⁻ NK cells*	6% ± 1%	2% ± 0.3%	<.0001
CD56^bright/CD3⁻ NK cells†	9% ± 2%	10% ± 2%	.84
CD56^dim/CD3⁻ NK cells†	90% ± 2%	89% ± 2%	.85
CD56⁺/CD3⁺ NK T cells*	1% ± 0.2%	1% ± 0.1%	.61
CD56⁻/CD3⁺ T cells*	40% ± 3%	20% ± 2%	<.0001
CD45⁺/SSC^hi (myeloid)*	21% ± 2%	36% ± 3%	.001
CD33⁺*	16% ± 2%	29% ± 2%	.002
MDSCs (CD33⁺/CD11b⁺/CD14⁻/HLA-DR^lo/−)*	0.1% ± 0.02%	6% ± 1%	<.0001

	Normal (n = 20)	MDS (n = 67)	P value
CD45⁺/SSC^lo (nonmyeloid)*	74% ± 2%	50% ± 2%	<.0001
CD45⁺/CD7⁺ lymphocytes*	54% ± 3%	25% ± 2%	<.0001
CD56⁺/CD3⁻ NK cells*	6% ± 1%	2% ± 0.3%	<.0001
CD56^bright/CD3⁻ NK cells†	9% ± 2%	10% ± 2%	.84
CD56^dim/CD3⁻ NK cells†	90% ± 2%	89% ± 2%	.85
CD56⁺/CD3⁺ NK T cells*	1% ± 0.2%	1% ± 0.1%	.61
CD56⁻/CD3⁺ T cells*	40% ± 3%	20% ± 2%	<.0001
CD45⁺/SSC^hi (myeloid)*	21% ± 2%	36% ± 3%	.001
CD33⁺*	16% ± 2%	29% ± 2%	.002
MDSCs (CD33⁺/CD11b⁺/CD14⁻/HLA-DR^lo/−)*	0.1% ± 0.02%	6% ± 1%	<.0001

SSC, side scatter.

Percent of all cells based on FSC/SSC gate excluding debris.

Percent of CD7⁺/CD56⁺/CD3⁻ NK cell population.