Patient characteristics
. | All . | CR1 . |
---|---|---|
. | (n = 201) (100%) . | (n = 84) (100%) . |
Age | ||
Median | 54 | 53 |
Range | 2-75 | 13-75 |
Age >60 y | 47 (23%) | 18 (22%) |
De novo AML/sAML/t-MN | ||
De novo | 123 (61) | 55 (65) |
sAML | 52 (26) | 19 (23) |
t-MN | 23 (11) | 7 (8) |
Missing | 3 (2) | 3 (4) |
Transplantation | ||
Upfront | 114 (57) | 84 (100) |
Salvage | 81 (40) | |
Missing | 6 (3) | |
MK | ||
No | 43 (21) | 17 (20) |
Yes | 155 (77) | 66 (79) |
Missing | 3 (2) | 1 (1) |
CK | ||
No | 18 (9) | 6 (7) |
Yes | 180 (90) | 77 (92) |
Missing | 3 (2) | 1 (1) |
Conditioning intensity | ||
Myeloablative | 70 (35) | 31 (37) |
Reduced intensity | 104 (52) | 35 (42) |
Nonmyeloablative | 18 (9) | 14 (17) |
Missing | 9 (4) | 4 (5) |
Donor source | ||
Sibling | 69 (34) | 29 (35) |
Matched unrelated donor (8/8) | 86 (43) | 36 (43) |
Partially matched unrelated donor | 36 (18) | 17 (20) |
Haploidentical | 8 (4) | 2 (2) |
Cord blood | 1 (1) | 0 (0) |
Missing | 1 (1) | 0 (0) |
Sex match | ||
Male recipient–female donor | 32 (16) | 14 (17) |
Any other | 109 (54) | 50 (60) |
Missing | 60 (30) | 20 (24) |
CMV status | ||
Neg-neg | 44 (22) | 20 (24) |
Pos recipient | 79 (39) | 38 (45) |
Neg recipient–pos donor | 18 (9) | 6 (7) |
Missing | 60 (30) | 20 (24) |
. | All . | CR1 . |
---|---|---|
. | (n = 201) (100%) . | (n = 84) (100%) . |
Age | ||
Median | 54 | 53 |
Range | 2-75 | 13-75 |
Age >60 y | 47 (23%) | 18 (22%) |
De novo AML/sAML/t-MN | ||
De novo | 123 (61) | 55 (65) |
sAML | 52 (26) | 19 (23) |
t-MN | 23 (11) | 7 (8) |
Missing | 3 (2) | 3 (4) |
Transplantation | ||
Upfront | 114 (57) | 84 (100) |
Salvage | 81 (40) | |
Missing | 6 (3) | |
MK | ||
No | 43 (21) | 17 (20) |
Yes | 155 (77) | 66 (79) |
Missing | 3 (2) | 1 (1) |
CK | ||
No | 18 (9) | 6 (7) |
Yes | 180 (90) | 77 (92) |
Missing | 3 (2) | 1 (1) |
Conditioning intensity | ||
Myeloablative | 70 (35) | 31 (37) |
Reduced intensity | 104 (52) | 35 (42) |
Nonmyeloablative | 18 (9) | 14 (17) |
Missing | 9 (4) | 4 (5) |
Donor source | ||
Sibling | 69 (34) | 29 (35) |
Matched unrelated donor (8/8) | 86 (43) | 36 (43) |
Partially matched unrelated donor | 36 (18) | 17 (20) |
Haploidentical | 8 (4) | 2 (2) |
Cord blood | 1 (1) | 0 (0) |
Missing | 1 (1) | 0 (0) |
Sex match | ||
Male recipient–female donor | 32 (16) | 14 (17) |
Any other | 109 (54) | 50 (60) |
Missing | 60 (30) | 20 (24) |
CMV status | ||
Neg-neg | 44 (22) | 20 (24) |
Pos recipient | 79 (39) | 38 (45) |
Neg recipient–pos donor | 18 (9) | 6 (7) |
Missing | 60 (30) | 20 (24) |
CMV, cytomegalovirus; neg, negative; pos, positive; t-MN, treatment-related myeloid neoplasm.