Multivariate analysis of 142 patients with available Ki67 value according to outcome
| Variable . | Score . | EFS . | PFS . | Survival . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| HR . | 95% CI . | P . | HR . | 95% CI . | P . | HR . | 95% CI . | P . | ||
| Age | Value | 0.99 | 0.96-1.03 | .776 | 0.99 | 0.96-1.03 | .804 | 1.01 | 0.96-1.06 | .670 |
| WHO Perform | 0-1/2-4 | 2.84 | 1.28-6.29 | .010 | 2.13 | 0.95-4.77 | .065 | 1.68 | 0.66- 4.29 | .275 |
| Sex | M/F | 1.19 | 0.64-2.24 | .582 | 1.12 | 0.63-2.26 | .575 | 0.82 | 0.36-1.89 | .647 |
| Stage | II/III-IV | 0.57 | 0.17-1.91 | .363 | 0.64 | 0.19-2.13 | .464 | 0.54 | 0.12-2.46 | .424 |
| Cytology | Common/blastoid | 1.78 | 0.96-3.30 | .067 | 2.11 | 1.15-3.88 | .015 | 3.43 | 1.74-6.77 | <.001 |
| Ki67 | 0-30/30+ | 1.17 | 0.61-2.23 | .638 | 1.22 | 0.63-2.35 | .558 | 1.44 | 0.66- 3.13 | .361 |
| LDH | Normal/elevated | 1.36 | 0.76-2.41 | .298 | 1.42 | 0.80-2.53 | .228 | 2.34 | 1.17-4.69 | .017 |
| WBC | 0-11/11+ | 1.43 | 0.81-2.54 | .218 | 1.51 | 0.85-2.67 | .161 | 1.62 | 0.83-3.18 | .157 |
| Variable . | Score . | EFS . | PFS . | Survival . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| HR . | 95% CI . | P . | HR . | 95% CI . | P . | HR . | 95% CI . | P . | ||
| Age | Value | 0.99 | 0.96-1.03 | .776 | 0.99 | 0.96-1.03 | .804 | 1.01 | 0.96-1.06 | .670 |
| WHO Perform | 0-1/2-4 | 2.84 | 1.28-6.29 | .010 | 2.13 | 0.95-4.77 | .065 | 1.68 | 0.66- 4.29 | .275 |
| Sex | M/F | 1.19 | 0.64-2.24 | .582 | 1.12 | 0.63-2.26 | .575 | 0.82 | 0.36-1.89 | .647 |
| Stage | II/III-IV | 0.57 | 0.17-1.91 | .363 | 0.64 | 0.19-2.13 | .464 | 0.54 | 0.12-2.46 | .424 |
| Cytology | Common/blastoid | 1.78 | 0.96-3.30 | .067 | 2.11 | 1.15-3.88 | .015 | 3.43 | 1.74-6.77 | <.001 |
| Ki67 | 0-30/30+ | 1.17 | 0.61-2.23 | .638 | 1.22 | 0.63-2.35 | .558 | 1.44 | 0.66- 3.13 | .361 |
| LDH | Normal/elevated | 1.36 | 0.76-2.41 | .298 | 1.42 | 0.80-2.53 | .228 | 2.34 | 1.17-4.69 | .017 |
| WBC | 0-11/11+ | 1.43 | 0.81-2.54 | .218 | 1.51 | 0.85-2.67 | .161 | 1.62 | 0.83-3.18 | .157 |
CI, confidence interval; F, female; HR, hazard ratio; M, male.