Results of patients studied in further detail with designations of stemlines and subclones, IGH translocations, and CNAs for 1q12, 1q21, 17p, and additional CNAs identified in RCs by FISH and SKY
| Patient # . | Clones . | IGH translocation . | CN 1q12 . | CN 1q21 . | CN 17p . | CNAs in RC . |
|---|---|---|---|---|---|---|
| Patients with der(1;8) | ||||||
| 1 | Stemline | Normal | 3 | 3 | 2 | MYC × 3,del(3q) |
| 31 | Stemline | Normal | 3 | 3 | 1 | MYC × 2 |
| Subclone | Normal | 4 | 4 | 1 | MYC × 3,del(7q) | |
| 52 | Stemline | t(4;14) | 3 | 3 | 2 | MYC × 3 |
| 62 | Stemline | t(14;16) | 8 | 8 | 1 | MYC × 8 |
| Patients with der(1;16) | ||||||
| 17 | Stemline | Normal | 5 | 5 | 1 | 16q11 × 4 |
| 59 | Stemline | t(4;14) | 8 | 8 | 1 | 16q11 × 8,del(11p) |
| Subclone | t(4;14) | 11 | 11 | 1 | 16q11 × 10,del(11p) | |
| 70 | Stemline | t(4;14) | 3 | 3 | 1 | 16q11 × 3 |
| Patients with complex sequential CNAs | ||||||
| 15 | Stemline | t(1;14) | 8 | 8 | 2 | BCL2 × 3, MLL × 4 |
| 32 | Stemline | t(4;14) | 8 | 8 | 1 | 1p36 × 5, FGFR3 × 5 |
| Patients with der(1;17) | ||||||
| 12 | Stemline | t(4;14) | 3 | 3 | 1 | TP53 × 1 |
| Subclone | t(4;14) | 2 | 2 | 1 | TP53 × 1 | |
| Subclone | t(4;14) | 3 | 3 | 1 | TP53 × 1 | |
| 18 | Stemline | t(11;14) | 3 | 3 | 1 | TP53 × 1 |
| 34 | Stemline | t(4;14) | 3 | 3 | 3 | TP53 × 3 |
| Subclone | t(4;14) | 4 | 4 | 2 | TP53 × 2,18q23 × 3 | |
| 36 | Stemline | t(4;14) | 4 | 4 | 1 | TP53 × 1 |
| Subclone | t(4;14) | 4 | 4 | 2 | TP53 × 2 | |
| 69 | Subclone | t(4;14) | 3 | 3 | 1 | TP53 × 1 |
| Subclone | t(4;14) | 2 | 2 | 1 | TP53 × 1 | |
| 77 | Stemline | t(4;14) | 3 | 3 | 1 | TP53 × 1 |
| 86 | Stemline | t(4;14) | 5 | 5 | 3 | TP53 × 3 |
| Subclone | t(4;14) | 5 | 5 | 2 | TP53 × 2 |
| Patient # . | Clones . | IGH translocation . | CN 1q12 . | CN 1q21 . | CN 17p . | CNAs in RC . |
|---|---|---|---|---|---|---|
| Patients with der(1;8) | ||||||
| 1 | Stemline | Normal | 3 | 3 | 2 | MYC × 3,del(3q) |
| 31 | Stemline | Normal | 3 | 3 | 1 | MYC × 2 |
| Subclone | Normal | 4 | 4 | 1 | MYC × 3,del(7q) | |
| 52 | Stemline | t(4;14) | 3 | 3 | 2 | MYC × 3 |
| 62 | Stemline | t(14;16) | 8 | 8 | 1 | MYC × 8 |
| Patients with der(1;16) | ||||||
| 17 | Stemline | Normal | 5 | 5 | 1 | 16q11 × 4 |
| 59 | Stemline | t(4;14) | 8 | 8 | 1 | 16q11 × 8,del(11p) |
| Subclone | t(4;14) | 11 | 11 | 1 | 16q11 × 10,del(11p) | |
| 70 | Stemline | t(4;14) | 3 | 3 | 1 | 16q11 × 3 |
| Patients with complex sequential CNAs | ||||||
| 15 | Stemline | t(1;14) | 8 | 8 | 2 | BCL2 × 3, MLL × 4 |
| 32 | Stemline | t(4;14) | 8 | 8 | 1 | 1p36 × 5, FGFR3 × 5 |
| Patients with der(1;17) | ||||||
| 12 | Stemline | t(4;14) | 3 | 3 | 1 | TP53 × 1 |
| Subclone | t(4;14) | 2 | 2 | 1 | TP53 × 1 | |
| Subclone | t(4;14) | 3 | 3 | 1 | TP53 × 1 | |
| 18 | Stemline | t(11;14) | 3 | 3 | 1 | TP53 × 1 |
| 34 | Stemline | t(4;14) | 3 | 3 | 3 | TP53 × 3 |
| Subclone | t(4;14) | 4 | 4 | 2 | TP53 × 2,18q23 × 3 | |
| 36 | Stemline | t(4;14) | 4 | 4 | 1 | TP53 × 1 |
| Subclone | t(4;14) | 4 | 4 | 2 | TP53 × 2 | |
| 69 | Subclone | t(4;14) | 3 | 3 | 1 | TP53 × 1 |
| Subclone | t(4;14) | 2 | 2 | 1 | TP53 × 1 | |
| 77 | Stemline | t(4;14) | 3 | 3 | 1 | TP53 × 1 |
| 86 | Stemline | t(4;14) | 5 | 5 | 3 | TP53 × 3 |
| Subclone | t(4;14) | 5 | 5 | 2 | TP53 × 2 |