Conditions or risk factors that should be considered when selecting the therapeutic approach in symptomatic outpatients with diagnosed IDDVT
| A) Conditions favoring full anticoagulation for 3 mo (as for proximal DVT) . | 
|---|
| Previous VTE events | 
| Idiopathic event | 
| Secondary event but with persistently hampered complete mobilization | 
| Event occurring during pregnancy or puerperium | 
| Distal thrombosis involving the popliteal trifurcation | 
| Thrombosis involving >1 calf vein | 
| Distal thrombosis present in both legs | 
| Active cancer or chemotherapy | 
| Presence of predisposing diseases (eg, inflammatory bowel diseases) | 
| Known thrombophilic alterations | 
| B) Conditions favoring shorter anticoagulation | 
| First thrombotic event, if: | 
| secondary to surgery or to other removable risk factors (eg, plasters, immobilization, trauma, long trip) | 
| event occurring during contraceptive or replacement hormonal therapy (provided the therapy has been interrupted) | 
| with subsequent full mobilization | 
| no difference between muscular or tibial-peroneal veins | 
| A) Conditions favoring full anticoagulation for 3 mo (as for proximal DVT) . | 
|---|
| Previous VTE events | 
| Idiopathic event | 
| Secondary event but with persistently hampered complete mobilization | 
| Event occurring during pregnancy or puerperium | 
| Distal thrombosis involving the popliteal trifurcation | 
| Thrombosis involving >1 calf vein | 
| Distal thrombosis present in both legs | 
| Active cancer or chemotherapy | 
| Presence of predisposing diseases (eg, inflammatory bowel diseases) | 
| Known thrombophilic alterations | 
| B) Conditions favoring shorter anticoagulation | 
| First thrombotic event, if: | 
| secondary to surgery or to other removable risk factors (eg, plasters, immobilization, trauma, long trip) | 
| event occurring during contraceptive or replacement hormonal therapy (provided the therapy has been interrupted) | 
| with subsequent full mobilization | 
| no difference between muscular or tibial-peroneal veins |