Demographic and clinical baseline characteristics in survivors and nonsurvivors
| Characteristic . | Survivors (n = 228) . | Nonsurvivors (n = 47) . |
|---|---|---|
| Age, y (IQR) | 61 (50-74) | 72 (60-76)* |
| Gender (male) | 144 (63%) | 29 (61%) |
| Referring specialty | ||
| Cardiology | 13 (5%) | 11 (23%) |
| Internal medicine | 39 (17%) | 14 (29%) |
| Neurology | 23 (10%) | 3 (6%) |
| Neurosurgery | 22 (10%) | 5 (10%) |
| Cardiopulmonary surgery | 19 (8%) | 3 (6%) |
| Surgery | 78 (34%) | 7 (15%) |
| Other | 34 (15%) | 4 (8%) |
| Inflammation/infection | ||
| Proven infection | 89 (39%) | 22 (46%)* |
| Sepsis | 5 (2%) | 0 (0%) |
| Severe sepsis | 44 (19%) | 7 (15%) |
| Septic shock | 40 (18%) | 15 (32%)† |
| Body temperature, °C (SD) | 38.2 (±1.1) | 38.1 (±1.5) |
| CRP, mg/mL (IQR) | 185 (106-281) | 184 (101-306) |
| PCT, μg/mL (IQR) | 1.15 (0.35-4.42) | 4.04 (0.59-9.8)* |
| Severity of illness | ||
| Mechanical ventilation | 146 (64%) | 28 (60%) |
| APACHE-IV score (IQR) | 72 (56-92) | 117 (96-136)† |
| Hemostasis | ||
| Prothrombin time, s (IQR) | 17.3 (15.5-22.6) | 14.8 (14.4-18) |
| Platelet count, × 109/L (IQR) | 178 (115-262) | 170 (90-336) |
| D-dimer, μg/mL (IQR) | 3.0 (1.8-5.1) | 4.6 (2.9-5.6) |
| Characteristic . | Survivors (n = 228) . | Nonsurvivors (n = 47) . |
|---|---|---|
| Age, y (IQR) | 61 (50-74) | 72 (60-76)* |
| Gender (male) | 144 (63%) | 29 (61%) |
| Referring specialty | ||
| Cardiology | 13 (5%) | 11 (23%) |
| Internal medicine | 39 (17%) | 14 (29%) |
| Neurology | 23 (10%) | 3 (6%) |
| Neurosurgery | 22 (10%) | 5 (10%) |
| Cardiopulmonary surgery | 19 (8%) | 3 (6%) |
| Surgery | 78 (34%) | 7 (15%) |
| Other | 34 (15%) | 4 (8%) |
| Inflammation/infection | ||
| Proven infection | 89 (39%) | 22 (46%)* |
| Sepsis | 5 (2%) | 0 (0%) |
| Severe sepsis | 44 (19%) | 7 (15%) |
| Septic shock | 40 (18%) | 15 (32%)† |
| Body temperature, °C (SD) | 38.2 (±1.1) | 38.1 (±1.5) |
| CRP, mg/mL (IQR) | 185 (106-281) | 184 (101-306) |
| PCT, μg/mL (IQR) | 1.15 (0.35-4.42) | 4.04 (0.59-9.8)* |
| Severity of illness | ||
| Mechanical ventilation | 146 (64%) | 28 (60%) |
| APACHE-IV score (IQR) | 72 (56-92) | 117 (96-136)† |
| Hemostasis | ||
| Prothrombin time, s (IQR) | 17.3 (15.5-22.6) | 14.8 (14.4-18) |
| Platelet count, × 109/L (IQR) | 178 (115-262) | 170 (90-336) |
| D-dimer, μg/mL (IQR) | 3.0 (1.8-5.1) | 4.6 (2.9-5.6) |
Data are presented as counts and percentages unless stated otherwise. Body temperature is presented as mean with standard deviation.
APACHE-IV, Acute Physiology and Chronic Health Evaluation IV severity of illness model; CRP, C-reactive protein; SD, standard deviation; s, seconds; y, year.
P < .05.
P < .01.