Characteristics of severe malaria patients by Hp genotype
| Characteristic . | Hp 1-1 . | Hp 2-1 . | Hp 2-2 . | |
|---|---|---|---|---|
| No. (%) | 312 (31.3) | 423 (42.5) | 261 (26.2) | |
| Median age, mo (IQR) | 27.4 (15.2-43.6) | 26.8 (15.2-41.4) | 27.5 (14.7-41.6) | |
| Male gender, no. (%) | 156 (50.0) | 203 (48.0) | 133 (51.0) | |
| Ethnic group, no. (%) | Giriama | 168 (53.9) | 225 (53.2) | 157 (60.2) |
| Chonyi | 82 (26.3) | 119 (28.1) | 56 (21.5) | |
| Kauma | 35 (11.2) | 41 (9.7) | 21 (8.1) | |
| Other Mijikenda | 19 (6.1) | 21 (5.0) | 24 (9.2) | |
| Non-Mijikenda | 8 (2.6) | 17 (4.0) | 3 (1.2) | |
| HbS type no. (%) (n = 990) | Hb AA | 300 (96.5) | 408 (97.6) | 254 (97.3) |
| Hb AS | 10 (3.2) | 7 (1.7) | 5 (1.9) | |
| Hb SS | 1 (0.3) | 3 (0.7) | 2 (0.8) | |
| α+Thalassemia genotype no. (%) | αα/αα | 126 (40.4) | 170 (40.2) | 102 (39.1) |
| -α/αα | 150 (48.1) | 203 (48.0) | 128 (49.0) | |
| -α/-α | 36 (11.5) | 50 (11.8) | 31 (11.9) | |
| Body mass index (n = 893)* | 10.6 (10.2-11.0) | 10.2 (9.9-10.6) | 10.3 (9.9-10.7) | |
| Parasitemia, log10 value, µL (n = 988) | 4.58 (4.45-4.71) | 4.64 (4.53-4.75) | 4.67 (4.54-4.81) | |
| Hb, g/dL (n = 993) | 6.6 (6.3-6.9) | 6.6 (6.4-6.8) | 6.7 (6.4-7.0) | |
| Characteristic . | Hp 1-1 . | Hp 2-1 . | Hp 2-2 . | |
|---|---|---|---|---|
| No. (%) | 312 (31.3) | 423 (42.5) | 261 (26.2) | |
| Median age, mo (IQR) | 27.4 (15.2-43.6) | 26.8 (15.2-41.4) | 27.5 (14.7-41.6) | |
| Male gender, no. (%) | 156 (50.0) | 203 (48.0) | 133 (51.0) | |
| Ethnic group, no. (%) | Giriama | 168 (53.9) | 225 (53.2) | 157 (60.2) |
| Chonyi | 82 (26.3) | 119 (28.1) | 56 (21.5) | |
| Kauma | 35 (11.2) | 41 (9.7) | 21 (8.1) | |
| Other Mijikenda | 19 (6.1) | 21 (5.0) | 24 (9.2) | |
| Non-Mijikenda | 8 (2.6) | 17 (4.0) | 3 (1.2) | |
| HbS type no. (%) (n = 990) | Hb AA | 300 (96.5) | 408 (97.6) | 254 (97.3) |
| Hb AS | 10 (3.2) | 7 (1.7) | 5 (1.9) | |
| Hb SS | 1 (0.3) | 3 (0.7) | 2 (0.8) | |
| α+Thalassemia genotype no. (%) | αα/αα | 126 (40.4) | 170 (40.2) | 102 (39.1) |
| -α/αα | 150 (48.1) | 203 (48.0) | 128 (49.0) | |
| -α/-α | 36 (11.5) | 50 (11.8) | 31 (11.9) | |
| Body mass index (n = 893)* | 10.6 (10.2-11.0) | 10.2 (9.9-10.6) | 10.3 (9.9-10.7) | |
| Parasitemia, log10 value, µL (n = 988) | 4.58 (4.45-4.71) | 4.64 (4.53-4.75) | 4.67 (4.54-4.81) | |
| Hb, g/dL (n = 993) | 6.6 (6.3-6.9) | 6.6 (6.4-6.8) | 6.7 (6.4-7.0) | |
Numbers (with percentages) are presented for categorical variables. Geometric means are presented with 95% confidence intervals (CIs) for continuous variables.
Due to severity of illness, a proportion of children did not have height measured.