Table 1 Quantification of wire injury... | American Society of Hematology

Table 1

Quantification of wire injury recovery

		Genotype			P value
Parameter		WT	PRCP^gt/gt	DKO	WT vs PRCP^gt/gt	PRCP^gt/gt vs DKO	WT vs DKO
Thickness	Media (μm²)	43 710 ± 13 280 (n = 40)	39 380 ± 17 600 (n = 45)	43 510 ± 16 330 (n = 23)	ns	ns	ns
	Intima (μm²)	11 040 ± 10 550 (n = 40)	31 790 ± 43 670 (n = 45)	15 320 ± 12 540 (n = 23)	*	ns	ns
	Int./Med (ratio)	0.25 ± 0.20 (n = 40)	0.77 ± 0.92 (n = 45)	0.33 ± 0.26 (n = 23)	†	‡	ns
CD45 (% area)	Intima	9.0 ± 4.1 (n = 6)	39.6 ± 19.0 (n = 6)	22.1 ± 19.9 (n = 6)	*	ns	ns
	Media	7.7 ± 8.2 (n = 6)	50.9 ± 28.6 (n = 6)	15.5 ± 16.3 (n = 6)	*	‡	ns
Ki-67	Intima	24.0 ± 16.7 (n = 5)	68.1 ± 18.2 (n = 4)	31.4 ± 18.1 (n = 5)	*	‡	ns
	Media	11.0 ± 14.6 (n = 5)	56.4 ± 29.6 (n = 4)	15.9 ± 5.3 (n = 5)	*	‡	ns

		Genotype			P value
Parameter		WT	PRCP^gt/gt	DKO	WT vs PRCP^gt/gt	PRCP^gt/gt vs DKO	WT vs DKO
Thickness	Media (μm²)	43 710 ± 13 280 (n = 40)	39 380 ± 17 600 (n = 45)	43 510 ± 16 330 (n = 23)	ns	ns	ns
	Intima (μm²)	11 040 ± 10 550 (n = 40)	31 790 ± 43 670 (n = 45)	15 320 ± 12 540 (n = 23)	*	ns	ns
	Int./Med (ratio)	0.25 ± 0.20 (n = 40)	0.77 ± 0.92 (n = 45)	0.33 ± 0.26 (n = 23)	†	‡	ns
CD45 (% area)	Intima	9.0 ± 4.1 (n = 6)	39.6 ± 19.0 (n = 6)	22.1 ± 19.9 (n = 6)	*	ns	ns
	Media	7.7 ± 8.2 (n = 6)	50.9 ± 28.6 (n = 6)	15.5 ± 16.3 (n = 6)	*	‡	ns
Ki-67	Intima	24.0 ± 16.7 (n = 5)	68.1 ± 18.2 (n = 4)	31.4 ± 18.1 (n = 5)	*	‡	ns
	Media	11.0 ± 14.6 (n = 5)	56.4 ± 29.6 (n = 4)	15.9 ± 5.3 (n = 5)	*	‡	ns

P values for one-way analysis of variance with Bonferroni correction.

DKO, PRCP^gt/gt/MRP-14^−/−; ns, not significant, P > .05.

*P < .01.

P < .001.

P < .05.