Clinical characteristics of MM patients
Patient no. . | Disease status at time of sampling . | Gender . | Response to bortezomib . | Bz (5 nM) . | Specific viability ex vivo (%) FK866 (3 nM) . | Combination (CI) . |
---|---|---|---|---|---|---|
1 | Diagnosis | M | Sensitive | 66 | 72.4 | 41 (0.8) |
2 | Relapse | F | Sensitive | 54.4 | 68.8 | 35.6 (0.9) |
3 | Relapse | M | Resistant | 74.2 | 74.1 | 54.8 (0.8) |
4 | Refractory | F | Resistant | 79.5 | 72.4 | 55.2 (0.7) |
5 | Refractory | F | Resistant | 74.4 | 82.5 | 54.4 (0.5) |
6 | Relapse | F | Sensitive | 26 | 40 | 0.5 (0.3) |
7 | Diagnosis | M | Sensitive | 63.9 | 84.5 | 46.48 (0.6) |
8 | Relapse | M | Resistant | 89.6 | 88 | 73.4 (0.1) |
9 | Relapse | M | Sensitive | 57 | 44.5 | 13 (0.7) |
10 | Refractory | F | Resistant | 93 | 89.1 | 63.4 (0.5) |
11 | Refractory | F | Resistant | 92.4 | 92.4 | 69.2 (0.5) |
Patient no. . | Disease status at time of sampling . | Gender . | Response to bortezomib . | Bz (5 nM) . | Specific viability ex vivo (%) FK866 (3 nM) . | Combination (CI) . |
---|---|---|---|---|---|---|
1 | Diagnosis | M | Sensitive | 66 | 72.4 | 41 (0.8) |
2 | Relapse | F | Sensitive | 54.4 | 68.8 | 35.6 (0.9) |
3 | Relapse | M | Resistant | 74.2 | 74.1 | 54.8 (0.8) |
4 | Refractory | F | Resistant | 79.5 | 72.4 | 55.2 (0.7) |
5 | Refractory | F | Resistant | 74.4 | 82.5 | 54.4 (0.5) |
6 | Relapse | F | Sensitive | 26 | 40 | 0.5 (0.3) |
7 | Diagnosis | M | Sensitive | 63.9 | 84.5 | 46.48 (0.6) |
8 | Relapse | M | Resistant | 89.6 | 88 | 73.4 (0.1) |
9 | Relapse | M | Sensitive | 57 | 44.5 | 13 (0.7) |
10 | Refractory | F | Resistant | 93 | 89.1 | 63.4 (0.5) |
11 | Refractory | F | Resistant | 92.4 | 92.4 | 69.2 (0.5) |
Bz, bortezomib.