Table 1

Clinical characteristics of MM patients

Patient no.Disease status at time of samplingGenderResponse to bortezomibBz (5 nM)Specific viability ex vivo (%) FK866 (3 nM)Combination (CI)
Diagnosis Sensitive 66 72.4 41 (0.8) 
Relapse Sensitive 54.4 68.8 35.6 (0.9) 
Relapse Resistant 74.2 74.1 54.8 (0.8) 
Refractory Resistant 79.5 72.4 55.2 (0.7) 
Refractory Resistant 74.4 82.5 54.4 (0.5) 
Relapse Sensitive 26 40 0.5 (0.3) 
Diagnosis Sensitive 63.9 84.5 46.48 (0.6) 
Relapse Resistant 89.6 88 73.4 (0.1) 
Relapse Sensitive 57 44.5 13 (0.7) 
10 Refractory Resistant 93 89.1 63.4 (0.5) 
11 Refractory Resistant 92.4 92.4 69.2 (0.5) 
Patient no.Disease status at time of samplingGenderResponse to bortezomibBz (5 nM)Specific viability ex vivo (%) FK866 (3 nM)Combination (CI)
Diagnosis Sensitive 66 72.4 41 (0.8) 
Relapse Sensitive 54.4 68.8 35.6 (0.9) 
Relapse Resistant 74.2 74.1 54.8 (0.8) 
Refractory Resistant 79.5 72.4 55.2 (0.7) 
Refractory Resistant 74.4 82.5 54.4 (0.5) 
Relapse Sensitive 26 40 0.5 (0.3) 
Diagnosis Sensitive 63.9 84.5 46.48 (0.6) 
Relapse Resistant 89.6 88 73.4 (0.1) 
Relapse Sensitive 57 44.5 13 (0.7) 
10 Refractory Resistant 93 89.1 63.4 (0.5) 
11 Refractory Resistant 92.4 92.4 69.2 (0.5) 

Bz, bortezomib.

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