Cohort 3 MDASI-CML symptom scores and QOL ratings
| Item . | Mean (SD) . | |
|---|---|---|
| Test, n = 152 . | Retest, n = 140 . | |
| Fatigue (tiredness) | 2.67 (2.53) | 2.53 (2.34) |
| Muscle soreness and cramping* | 2.23 (2.58)‡ | 2.07 (2.25)‡ |
| Feeling drowsy (sleepy) | 2.18 (2.29) | 2.14 (2.21) |
| Disturbed sleep | 2.13 (2.44) | 2.06 (2.50) |
| Problem with remembering things | 1.82 (1.96) | 1.78 (1.91) |
| Pain | 1.75 (2.49) | 1.57 (2.36) |
| Swelling of the hands, legs, feet, abdomen, and around the eyes* | 1.74 (2.13)‡ | 1.64 (2.02)‡ |
| Feeling of malaise (not feeling well)* | 1.72 (2.14)‡ | 1.50 (1.93)‡ |
| Feeling distressed (upset) | 1.66 (2.26) | 1.33 (1.90) |
| Having a dry mouth | 1.66 (2.25) | 1.50 (2.27) |
| Numbness or tingling | 1.47 (2.20) | 1.28 (1.93) |
| Feeling sad | 1.43 (2.14) | 1.36 (2.00) |
| Shortness of breath | 1.28 (1.74) | 1.09 (1.60) |
| Rash or skin changes* | 1.25 (1.77)‡ | 1.19 (1.47)‡ |
| Headache† | 1.21 (1.78)‡ | 1.20 (1.84)‡ |
| Diarrhea* | 1.18 (2.10)‡ | 0.96 (1.86)‡ |
| Bruising easily and bleeding* | 1.14 (1.79)‡ | 0.85 (1.30)‡ |
| Nausea | 0.81 (1.63) | 0.55 (1.18) |
| Problem with lack of appetite | 0.74 (1.54) | 0.58 (1.30) |
| Vomiting | 0.36 (0.93) | 0.20 (0.65) |
| Mean combined core symptoms | 1.54 (1.45) | 1.38 (1.32) |
| Mean combined 5 most severe core symptoms | 2.11 (1.92) | 2.03 (1.82) |
| Mean combined CML symptoms | 1.49 (1.39) | 1.34 (1.22) |
| Mean combined 5 most severe CML symptoms | 1.63 (1.51) | 1.52 (1.38) |
| Work (including work around the house) | 2.01 (2.37) | 1.78 (2.17) |
| General activity | 1.81 (2.23) | 1.48 (1.96) |
| Walking | 1.66 (2.31) | 1.36 (2.06) |
| Mood | 1.62 (2.10) | 1.39 (2.04) |
| Enjoyment of life | 1.55 (2.20) | 1.23 (1.93) |
| Relations with other people | 1.25 (1.92) | 1.02 (1.67) |
| Mean combined interference items | 1.65 (1.94) | 1.38 (1.71) |
| Mean combined physical interference items | 1.83 (2.15) | 1.54 (1.89) |
| Mean combined affective interference items | 1.47 (1.94) | 1.21 (1.76) |
| Single-item QOL | 8.14 (2.05) | Not done |
| Item . | Mean (SD) . | |
|---|---|---|
| Test, n = 152 . | Retest, n = 140 . | |
| Fatigue (tiredness) | 2.67 (2.53) | 2.53 (2.34) |
| Muscle soreness and cramping* | 2.23 (2.58)‡ | 2.07 (2.25)‡ |
| Feeling drowsy (sleepy) | 2.18 (2.29) | 2.14 (2.21) |
| Disturbed sleep | 2.13 (2.44) | 2.06 (2.50) |
| Problem with remembering things | 1.82 (1.96) | 1.78 (1.91) |
| Pain | 1.75 (2.49) | 1.57 (2.36) |
| Swelling of the hands, legs, feet, abdomen, and around the eyes* | 1.74 (2.13)‡ | 1.64 (2.02)‡ |
| Feeling of malaise (not feeling well)* | 1.72 (2.14)‡ | 1.50 (1.93)‡ |
| Feeling distressed (upset) | 1.66 (2.26) | 1.33 (1.90) |
| Having a dry mouth | 1.66 (2.25) | 1.50 (2.27) |
| Numbness or tingling | 1.47 (2.20) | 1.28 (1.93) |
| Feeling sad | 1.43 (2.14) | 1.36 (2.00) |
| Shortness of breath | 1.28 (1.74) | 1.09 (1.60) |
| Rash or skin changes* | 1.25 (1.77)‡ | 1.19 (1.47)‡ |
| Headache† | 1.21 (1.78)‡ | 1.20 (1.84)‡ |
| Diarrhea* | 1.18 (2.10)‡ | 0.96 (1.86)‡ |
| Bruising easily and bleeding* | 1.14 (1.79)‡ | 0.85 (1.30)‡ |
| Nausea | 0.81 (1.63) | 0.55 (1.18) |
| Problem with lack of appetite | 0.74 (1.54) | 0.58 (1.30) |
| Vomiting | 0.36 (0.93) | 0.20 (0.65) |
| Mean combined core symptoms | 1.54 (1.45) | 1.38 (1.32) |
| Mean combined 5 most severe core symptoms | 2.11 (1.92) | 2.03 (1.82) |
| Mean combined CML symptoms | 1.49 (1.39) | 1.34 (1.22) |
| Mean combined 5 most severe CML symptoms | 1.63 (1.51) | 1.52 (1.38) |
| Work (including work around the house) | 2.01 (2.37) | 1.78 (2.17) |
| General activity | 1.81 (2.23) | 1.48 (1.96) |
| Walking | 1.66 (2.31) | 1.36 (2.06) |
| Mood | 1.62 (2.10) | 1.39 (2.04) |
| Enjoyment of life | 1.55 (2.20) | 1.23 (1.93) |
| Relations with other people | 1.25 (1.92) | 1.02 (1.67) |
| Mean combined interference items | 1.65 (1.94) | 1.38 (1.71) |
| Mean combined physical interference items | 1.83 (2.15) | 1.54 (1.89) |
| Mean combined affective interference items | 1.47 (1.94) | 1.21 (1.76) |
| Single-item QOL | 8.14 (2.05) | Not done |