Clinical features (N = 89)
| Characteristic . | No. . | % . |
|---|---|---|
| Time from symptoms to diagnosis, mo | ||
| Median | 37.4 | |
| Range | 0-374.2 | |
| Chief concern at diagnosis | ||
| Anemia of undetermined origin | 31 | 35 |
| Acrocyanosis | 21 | 24 |
| Fatigue | 19 | 21 |
| Weakness | 4 | 4 |
| Dyspnea on exertion | 3 | 3 |
| Hemoglobinuria | 3 | 3 |
| Symptoms during disease course | ||
| Acrocyanosis | 39 | 44 |
| Fatigue | 36 | 40 |
| Dyspnea on exertion | 19 | 21 |
| Hemoglobinuria | 13 | 15 |
| Weakness | 9 | 10 |
| Weight loss | 9 | 10 |
| Identification of triggers | ||
| Cold | 35 | 39 |
| Other | 20 | 22 |
| Received drug therapy | 73 | 82 |
| Received transfusion | 36 | 40 |
| Overall survival, y | ||
| Median | 10.6 | |
| Range | 0.0-29.9 | |
| Survived 5 y after diagnosis | 68 | 76 |
| Characteristic . | No. . | % . |
|---|---|---|
| Time from symptoms to diagnosis, mo | ||
| Median | 37.4 | |
| Range | 0-374.2 | |
| Chief concern at diagnosis | ||
| Anemia of undetermined origin | 31 | 35 |
| Acrocyanosis | 21 | 24 |
| Fatigue | 19 | 21 |
| Weakness | 4 | 4 |
| Dyspnea on exertion | 3 | 3 |
| Hemoglobinuria | 3 | 3 |
| Symptoms during disease course | ||
| Acrocyanosis | 39 | 44 |
| Fatigue | 36 | 40 |
| Dyspnea on exertion | 19 | 21 |
| Hemoglobinuria | 13 | 15 |
| Weakness | 9 | 10 |
| Weight loss | 9 | 10 |
| Identification of triggers | ||
| Cold | 35 | 39 |
| Other | 20 | 22 |
| Received drug therapy | 73 | 82 |
| Received transfusion | 36 | 40 |
| Overall survival, y | ||
| Median | 10.6 | |
| Range | 0.0-29.9 | |
| Survived 5 y after diagnosis | 68 | 76 |