Distribution of clinical events among LAC-positive and LAC-negative patients
| Clinical event . | LAC negative, n = 340 (%) . | LAC positive, n = 62 (%) . | P (95% CI) . |
|---|---|---|---|
| TE (idiopathic) | 4 (1.2) | 10 (16.1) | <.001 (0.085-0.182) |
| TE (with risk factor*) | 6 (1.8) | 11 (17.7) | <.001 (0.113-0.217) |
| ≥1 stillbirth | 23/326 (7.1) | 19/50 (38.0) | <.001 (0.283-0.477) |
| ≥2 early SA | 234/326 (71.8) | 14/50 (28.0) | <.001 (0.287-0.569) |
| IUGR | 3/326 (0.9) | 9/50 (18.0) | <.001 (0.119-0.223) |
| HELLP | 1/326 (0.3) | 6/50 (12.0) | <.001 (0.077-0.157) |
| Preeclampsia | 6/326 (1.8) | 3/50 (6.0) | .186 (−0.087-0.003) |
| ≥1 live birth | 230/326 (70.6) | 36/50 (72.0) | .972 (−0.149 to 0.121) |
| No adverse obstetric events | 31/326 (9.5) | 5/50 (10.0) | .884 (−0.092 to 0.082) |
| Clinical event . | LAC negative, n = 340 (%) . | LAC positive, n = 62 (%) . | P (95% CI) . |
|---|---|---|---|
| TE (idiopathic) | 4 (1.2) | 10 (16.1) | <.001 (0.085-0.182) |
| TE (with risk factor*) | 6 (1.8) | 11 (17.7) | <.001 (0.113-0.217) |
| ≥1 stillbirth | 23/326 (7.1) | 19/50 (38.0) | <.001 (0.283-0.477) |
| ≥2 early SA | 234/326 (71.8) | 14/50 (28.0) | <.001 (0.287-0.569) |
| IUGR | 3/326 (0.9) | 9/50 (18.0) | <.001 (0.119-0.223) |
| HELLP | 1/326 (0.3) | 6/50 (12.0) | <.001 (0.077-0.157) |
| Preeclampsia | 6/326 (1.8) | 3/50 (6.0) | .186 (−0.087-0.003) |
| ≥1 live birth | 230/326 (70.6) | 36/50 (72.0) | .972 (−0.149 to 0.121) |
| No adverse obstetric events | 31/326 (9.5) | 5/50 (10.0) | .884 (−0.092 to 0.082) |
SA, spontaneous abortion.
Predisposing events for thrombosis: oral contraception, surgery, and postpartum period.