Table 1 Clinical history of patients... | American Society of Hematology

Table 1

Clinical history of patients receiving anti-CD19-CAR T cells

Patient	Age	Gender	Malignancy	Type of donor with most recent transplant*	GVHD at any time after most recent transplant	Number of DLIs from most recent transplant donor	Time from most recent standard DLI until CAR T-cell infusion (mo)	Cell dose of most recent standard DLI before CAR T-cell infusion (CD3⁺ cells per kg)	Antimalignancy response after most recent standard DLI before CAR T-cell infusion
1	66	M	CLL	URD	Yes	5	5	5.9 × 10⁷†	SD
2	44	M	DLBCL	MSD	Yes	1	3	2.5 × 10⁷†	SD
3	55	M	CLL	MSD	No	14	8	2.9 × 10⁷†	PD
4	49	M	DLBCL	MSD	Yes	1	2	1.1 × 10⁷	SD
5‡	44	F	CLL	URD	Yes	5	13	1.0 × 10⁸	SD
6	48	M	MCL	MSD	No	3	15	5.0 × 10⁷†	PR
7§	48	M	CLL	URD	No	1	5	1.0 × 10⁷	PD
8	63	F	MCL	MSD	Yes	1	12	3.6 × 10⁷†	PR
9	57	M	MCL	URD	Yes	2	9	1 × 10⁶	SD
10	50	M	MCL	MSD	No	6	25	3.1 × 10⁷†	SD

Patient	Age	Gender	Malignancy	Type of donor with most recent transplant*	GVHD at any time after most recent transplant	Number of DLIs from most recent transplant donor	Time from most recent standard DLI until CAR T-cell infusion (mo)	Cell dose of most recent standard DLI before CAR T-cell infusion (CD3⁺ cells per kg)	Antimalignancy response after most recent standard DLI before CAR T-cell infusion
1	66	M	CLL	URD	Yes	5	5	5.9 × 10⁷†	SD
2	44	M	DLBCL	MSD	Yes	1	3	2.5 × 10⁷†	SD
3	55	M	CLL	MSD	No	14	8	2.9 × 10⁷†	PD
4	49	M	DLBCL	MSD	Yes	1	2	1.1 × 10⁷	SD
5‡	44	F	CLL	URD	Yes	5	13	1.0 × 10⁸	SD
6	48	M	MCL	MSD	No	3	15	5.0 × 10⁷†	PR
7§	48	M	CLL	URD	No	1	5	1.0 × 10⁷	PD
8	63	F	MCL	MSD	Yes	1	12	3.6 × 10⁷†	PR
9	57	M	MCL	URD	Yes	2	9	1 × 10⁶	SD
10	50	M	MCL	MSD	No	6	25	3.1 × 10⁷†	SD

DLBCL, diffuse large B-cell lymphoma; MCL, mantle cell lymphoma; PD, progressive disease; PR, partial remission; SD, stable disease.

All URD recipients were 10/10 HLA-matched with their donor.

The indicated DLIs were given with chemotherapy and/or monoclonal antibodies.

Patient 5 received 3 allogeneic stem cell transplants.

Patient 7 received 2 allogeneic stem cell transplants; information on the most recent transplants of these patients is presented.