Immunohistochemical and molecular findings in 10 cases of indolent T-LPD of the GI tract
Case . | CD3 . | CD4/CD8 . | CD2 . | CD5 . | CD7 . | CD30 . | CD56 . | TIA1 . | GRZB . | TCR-BF1 . | TCR-G . | Ki67, % . | EBER . | TCR-PCR . |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | + | −/+ | + | + | + | − | − | + | − | + | NA | 5-10 | − | Clonal |
2 | + | −/+ | + | + | + | − | − | + | − | NA | NA | 5-10 | − | Clonal |
3 | + | −/+ | NA | + | NA | NA | − | + | − | + | − | NA | − | Clonal |
4 | + | −/+ | + | + | + | − | − | + | NA | + | − | 5 | − | Clonal |
5 | + | −/− | + | − | + | − | − | − | NA | + | − | NA | − | Clonal |
6 | + | +/− | + | − | − | − | − | − | − | + | − | NA | NA | Clonal |
7 | + | −/+ | NA | + | − | NA | − | + | − | NA | NA | 5 | − | Clonal |
8 | + | −/+ | NA | + | − | − | − | + | − | + | − | 5 | − | Clonal |
9 | + | −/+ | + | + | + | − | − | NA | − | NA | NA | 5 | NA | Clonal |
10 | + | −/+ | + | + | + | − | − | + | + | + | NA | 5 | − | Clonal |
Case . | CD3 . | CD4/CD8 . | CD2 . | CD5 . | CD7 . | CD30 . | CD56 . | TIA1 . | GRZB . | TCR-BF1 . | TCR-G . | Ki67, % . | EBER . | TCR-PCR . |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | + | −/+ | + | + | + | − | − | + | − | + | NA | 5-10 | − | Clonal |
2 | + | −/+ | + | + | + | − | − | + | − | NA | NA | 5-10 | − | Clonal |
3 | + | −/+ | NA | + | NA | NA | − | + | − | + | − | NA | − | Clonal |
4 | + | −/+ | + | + | + | − | − | + | NA | + | − | 5 | − | Clonal |
5 | + | −/− | + | − | + | − | − | − | NA | + | − | NA | − | Clonal |
6 | + | +/− | + | − | − | − | − | − | − | + | − | NA | NA | Clonal |
7 | + | −/+ | NA | + | − | NA | − | + | − | NA | NA | 5 | − | Clonal |
8 | + | −/+ | NA | + | − | − | − | + | − | + | − | 5 | − | Clonal |
9 | + | −/+ | + | + | + | − | − | NA | − | NA | NA | 5 | NA | Clonal |
10 | + | −/+ | + | + | + | − | − | + | + | + | NA | 5 | − | Clonal |
EBER, Epstein-Barr virus-encoded RNA; GRZB, granzyme B; NA, not available; TCR-BF1, T-cell receptor β F1; TCR-G, T-cell receptor γ; TCR-PCR, T-cell receptor-γ chain gene rearrangement by polymerase chain reaction; +, positive; −, negative.