Table 2

Comparison of pAKT expression between circulating and skin resident SS cells concurrently analyzed

SS patientsPTEN statuspAKT amount in circulating SS cells detected by WB*pAKT+ SS skin resident cells detected by IHC (%)
SS32 ML 5% 
SS39 ML 0.01 25% 
SS51 WT 0.26 40% 
SS53 ML 0.07 40% 
SS67 ML 0.5 30% 
HD WT 0.39 ± 0.12 0 
SS patientsPTEN statuspAKT amount in circulating SS cells detected by WB*pAKT+ SS skin resident cells detected by IHC (%)
SS32 ML 5% 
SS39 ML 0.01 25% 
SS51 WT 0.26 40% 
SS53 ML 0.07 40% 
SS67 ML 0.5 30% 
HD WT 0.39 ± 0.12 0 
*

Densitometric values calculated as pAKT/actin.

IHC for pAKT in healthy skin is shown in supplemental Figure 3.

Close Modal

or Create an Account

Close Modal
Close Modal