Table 2

Low density gene expression TaqMan array performed on tumor-infiltrating CD4+ lymphocytes from PyMT mice

GeneP value*FolddCtSD
Gm-csf <.05 2.0 8.8 0.83 
Il-13 <.05 1.8 7.6 0.89 
Ccr6 <.05 −1.8 12.8 0.91 
Il-6 <.05 −2.4 14.2 0.91 
Csf1r <.05 −2.4 12.0 1.15 
Pu.1 <.01 −3.3 13.1 0.73 
GeneP value*FolddCtSD
Gm-csf <.05 2.0 8.8 0.83 
Il-13 <.05 1.8 7.6 0.89 
Ccr6 <.05 −1.8 12.8 0.91 
Il-6 <.05 −2.4 14.2 0.91 
Csf1r <.05 −2.4 12.0 1.15 
Pu.1 <.01 −3.3 13.1 0.73 

The tumor-infiltrating CD4+ lymphocytes were sorted from PyMT mice reconstituted with miR-155/KD– or Ctrl LV–transduced HSPCs. N = 3 replicates, each representing a pool of 3 mice.

*

Shown are differentially regulated genes with P value < .05.

SD, standard deviation.

The fold change of the respective transcripts in the miR-155/KD group with respect to the control group is indicated (linear scale; “−” denotes fold-less expression in the miR-155/KD samples).

Raw expression data were normalized to Actinb (dCT).

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