Table 1

Characteristics of participating studies

Study name (reference)LocationPeriod of interview/ diagnosisCases (n = 1320)Controls (n = 6381)
No.% PartAge range (y)Tumor histologyClassificationTumor EBV statusNo.% PartSourceMatching
Epilymph (14) Spain, France, Italy, Germany, Ireland, Finland, Czech Republic 1998-2004 331 88 17-80 195 NS, 71 MC, 1 other WHO 18 positive, 27 negative (Spain only) 2540 81 Population registers (Italy and Germany) or hospitals (Spain, France, Ireland, Czech Republic) Individual (Germany, Czech Republic) or frequency (France, Ireland, Italy, Spain) by sex, age (5-y groups), and area of residence 
ELCCS North, East, and West Yorkshire, Lancashire, South Lakeland, Cornwall, South Devon, Dorset, South Hampshire, England 1998-2004 262 79 16-67 203 NS, 47 MC, 12 other ICD-O-3 48 positive, 116 negative 237 69 Randomly selected from population registers Individual by sex, date of birth, and area of residence 
SCALE (11) Denmark, Sweden 1999-2003 585 91 17-75 422 NS, 106 MC, 10 other WHO 142 positive, 383 negative 3187 71 Randomly selected from population registers Frequency by country, age (10-y groups), and sex 
Engela (13) Bordeaux, Brest, Caen, Lille, Nantes, Toulouse, France 2000-2004 142 97 18-71 106 NS, 18 MC, 3 other ICD-O-3 No data 417 93 Hospitals, with no history of hematologic neoplasm Individual by center, sex, age, and area of residence 
Study name (reference)LocationPeriod of interview/ diagnosisCases (n = 1320)Controls (n = 6381)
No.% PartAge range (y)Tumor histologyClassificationTumor EBV statusNo.% PartSourceMatching
Epilymph (14) Spain, France, Italy, Germany, Ireland, Finland, Czech Republic 1998-2004 331 88 17-80 195 NS, 71 MC, 1 other WHO 18 positive, 27 negative (Spain only) 2540 81 Population registers (Italy and Germany) or hospitals (Spain, France, Ireland, Czech Republic) Individual (Germany, Czech Republic) or frequency (France, Ireland, Italy, Spain) by sex, age (5-y groups), and area of residence 
ELCCS North, East, and West Yorkshire, Lancashire, South Lakeland, Cornwall, South Devon, Dorset, South Hampshire, England 1998-2004 262 79 16-67 203 NS, 47 MC, 12 other ICD-O-3 48 positive, 116 negative 237 69 Randomly selected from population registers Individual by sex, date of birth, and area of residence 
SCALE (11) Denmark, Sweden 1999-2003 585 91 17-75 422 NS, 106 MC, 10 other WHO 142 positive, 383 negative 3187 71 Randomly selected from population registers Frequency by country, age (10-y groups), and sex 
Engela (13) Bordeaux, Brest, Caen, Lille, Nantes, Toulouse, France 2000-2004 142 97 18-71 106 NS, 18 MC, 3 other ICD-O-3 No data 417 93 Hospitals, with no history of hematologic neoplasm Individual by center, sex, age, and area of residence 

% part, participation rate; MC, mixed cellularity; NS, nodular sclerosis; WHO, World Health Organization.

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