Table 5 Risk of venous thrombosis for... | American Society of Hematology

Table 5

Risk of venous thrombosis for high or low levels of protein S, according to family history

			OR (95% CI)*
	Patients, n	Controls, n	Overall	Overall minus†
Negative family history
Free protein S antigen
>97.5^th percentile (>139 U/dL)	936	2705	Reference	Reference
<2.5^th percentile (<53 U/dL)	24	70	0.75 (0.46-1.21)	1.95 (0.93-4.05)
Total protein S antigen
97.5^th-2.5^th percentile (68-146 U/dL)	964	2766	Reference	Reference
<2.5^th percentile (<68 U/dL)	21	72	0.65 (0.40-1.07)	1.41 (0.66-3.00)
Positive family history
Free protein S antigen
97.5^th-2.5^th percentile (53-139 U/dL)	524	2705	Reference	Reference
<2.5^th percentile (<53 U/dL)	10	70	0.86 (0.44-1.70)	0.92 (0.27-3.08)
Total protein S antigen
97.5^th-2.5^th percentile (68-146 U/dL)	540	2766	Reference	Reference
<2.5^th percentile (<68 U/dL)	12	72	1.00 (0.53-1.86)	1.08 (0.37-3.15)

			OR (95% CI)*
	Patients, n	Controls, n	Overall	Overall minus†
Negative family history
Free protein S antigen
>97.5^th percentile (>139 U/dL)	936	2705	Reference	Reference
<2.5^th percentile (<53 U/dL)	24	70	0.75 (0.46-1.21)	1.95 (0.93-4.05)
Total protein S antigen
97.5^th-2.5^th percentile (68-146 U/dL)	964	2766	Reference	Reference
<2.5^th percentile (<68 U/dL)	21	72	0.65 (0.40-1.07)	1.41 (0.66-3.00)
Positive family history
Free protein S antigen
97.5^th-2.5^th percentile (53-139 U/dL)	524	2705	Reference	Reference
<2.5^th percentile (<53 U/dL)	10	70	0.86 (0.44-1.70)	0.92 (0.27-3.08)
Total protein S antigen
97.5^th-2.5^th percentile (68-146 U/dL)	540	2766	Reference	Reference
<2.5^th percentile (<68 U/dL)	12	72	1.00 (0.53-1.86)	1.08 (0.37-3.15)

Adjusted for age and gender.

Estrogen users or pregnancy/puerperium.